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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TUBE1 All Species: 26.97
Human Site: S386 Identified Species: 45.64
UniProt: Q9UJT0 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UJT0 NP_057346.1 475 52932 S386 G W K T S L C S V P P V G H S
Chimpanzee Pan troglodytes Q8WP14 444 49773 V353 P N N V K T A V C D I P P R G
Rhesus Macaque Macaca mulatta XP_001085410 522 58040 S433 G W K T S L C S I P P V G H S
Dog Lupus familis XP_855214 604 66869 S515 G W K T S L C S V P P V G H S
Cat Felis silvestris
Mouse Mus musculus Q9D6T1 475 52634 S386 G W K T S L C S V P P V G H S
Rat Rattus norvegicus NP_001102006 400 44503 V312 W K T S L C S V P P V G H P H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505776 507 56739 S418 G W K T S L C S I P P V G H S
Chicken Gallus gallus XP_419781 475 52815 S386 G W K T S L C S V P P V G H S
Frog Xenopus laevis NP_001082338 472 52531 S384 G W K T G L C S V P P V G H S
Zebra Danio Brachydanio rerio NP_957279 271 29245 D183 V Y P T A E D D V I T S P Y N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394700 420 47075 G332 G T E A M K I G L C S V P P A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781720 474 52919 F374 R L R P S L N F I H W N T D G
Poplar Tree Populus trichocarpa
Maize Zea mays P18025 446 49944 V353 P N N V K S T V C D I P P H G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P05220 447 49850 L353 P N N V Q T A L C S I P P R G
Conservation
Percent
Protein Identity: 100 34.3 87.1 73.3 N.A. 91.1 75.7 N.A. 79 84.6 81.6 40.2 N.A. N.A. 42.3 N.A. 64.8
Protein Similarity: 100 53 89.2 76.6 N.A. 96.8 81 N.A. 87.3 93 91.5 50.5 N.A. N.A. 63.1 N.A. 80.4
P-Site Identity: 100 0 93.3 100 N.A. 100 6.6 N.A. 93.3 100 93.3 13.3 N.A. N.A. 13.3 N.A. 13.3
P-Site Similarity: 100 0 100 100 N.A. 100 13.3 N.A. 100 100 93.3 40 N.A. N.A. 33.3 N.A. 26.6
Percent
Protein Identity: N.A. 33 N.A. N.A. N.A. 32.4
Protein Similarity: N.A. 53.2 N.A. N.A. N.A. 53.2
P-Site Identity: N.A. 6.6 N.A. N.A. N.A. 0
P-Site Similarity: N.A. 6.6 N.A. N.A. N.A. 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 8 0 15 0 0 0 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 8 50 0 22 8 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 8 0 15 0 0 0 8 0 % D
% Glu: 0 0 8 0 0 8 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 58 0 0 0 8 0 0 8 0 0 0 8 50 0 29 % G
% His: 0 0 0 0 0 0 0 0 0 8 0 0 8 58 8 % H
% Ile: 0 0 0 0 0 0 8 0 22 8 22 0 0 0 0 % I
% Lys: 0 8 50 0 15 8 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 8 0 0 8 58 0 8 8 0 0 0 0 0 0 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 22 22 0 0 0 8 0 0 0 0 8 0 0 8 % N
% Pro: 22 0 8 8 0 0 0 0 8 58 50 22 36 15 0 % P
% Gln: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 0 8 0 0 0 0 0 0 0 0 0 0 15 0 % R
% Ser: 0 0 0 8 50 8 8 50 0 8 8 8 0 0 50 % S
% Thr: 0 8 8 58 0 15 8 0 0 0 8 0 8 0 0 % T
% Val: 8 0 0 22 0 0 0 22 43 0 8 58 0 0 0 % V
% Trp: 8 50 0 0 0 0 0 0 0 0 8 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _