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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TUBE1 All Species: 22.12
Human Site: T241 Identified Species: 37.44
UniProt: Q9UJT0 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UJT0 NP_057346.1 475 52932 T241 V K P K S L V T S S S G A L K
Chimpanzee Pan troglodytes Q8WP14 444 49773 D209 I D N E A L Y D I C S K T L K
Rhesus Macaque Macaca mulatta XP_001085410 522 58040 T288 V K P K S L V T S S S G A L K
Dog Lupus familis XP_855214 604 66869 T370 I K A K S L V T S S A G A V K
Cat Felis silvestris
Mouse Mus musculus Q9D6T1 475 52634 T241 V K P K S L I T S N M G A V K
Rat Rattus norvegicus NP_001102006 400 44503 K178 P V K K R H K K P F D A M N N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505776 507 56739 T273 L K P R S L I T S S E G G I R
Chicken Gallus gallus XP_419781 475 52815 T241 V K P N S L V T S S A G T A K
Frog Xenopus laevis NP_001082338 472 52531 S241 K P N S L V T S S K G G V K E
Zebra Danio Brachydanio rerio NP_957279 271 29245 D49 S S F F R N V D Q R R G Y G A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394700 420 47075 L198 V D I C N A Q L F Q D M N S I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781720 474 52919 Q234 T Y P S G S G Q V K G Q G S V
Poplar Tree Populus trichocarpa
Maize Zea mays P18025 446 49944 L217 I C F R T L K L T T P S F G D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P05220 447 49850 D209 I D N E A L Y D I C M R T L K
Conservation
Percent
Protein Identity: 100 34.3 87.1 73.3 N.A. 91.1 75.7 N.A. 79 84.6 81.6 40.2 N.A. N.A. 42.3 N.A. 64.8
Protein Similarity: 100 53 89.2 76.6 N.A. 96.8 81 N.A. 87.3 93 91.5 50.5 N.A. N.A. 63.1 N.A. 80.4
P-Site Identity: 100 26.6 100 73.3 N.A. 73.3 6.6 N.A. 53.3 73.3 13.3 13.3 N.A. N.A. 6.6 N.A. 6.6
P-Site Similarity: 100 46.6 100 93.3 N.A. 93.3 6.6 N.A. 86.6 80 33.3 13.3 N.A. N.A. 13.3 N.A. 6.6
Percent
Protein Identity: N.A. 33 N.A. N.A. N.A. 32.4
Protein Similarity: N.A. 53.2 N.A. N.A. N.A. 53.2
P-Site Identity: N.A. 6.6 N.A. N.A. N.A. 20
P-Site Similarity: N.A. 40 N.A. N.A. N.A. 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 15 8 0 0 0 0 15 8 29 8 8 % A
% Cys: 0 8 0 8 0 0 0 0 0 15 0 0 0 0 0 % C
% Asp: 0 22 0 0 0 0 0 22 0 0 15 0 0 0 8 % D
% Glu: 0 0 0 15 0 0 0 0 0 0 8 0 0 0 8 % E
% Phe: 0 0 15 8 0 0 0 0 8 8 0 0 8 0 0 % F
% Gly: 0 0 0 0 8 0 8 0 0 0 15 58 15 15 0 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 29 0 8 0 0 0 15 0 15 0 0 0 0 8 8 % I
% Lys: 8 43 8 36 0 0 15 8 0 15 0 8 0 8 50 % K
% Leu: 8 0 0 0 8 65 0 15 0 0 0 0 0 29 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 15 8 8 0 0 % M
% Asn: 0 0 22 8 8 8 0 0 0 8 0 0 8 8 8 % N
% Pro: 8 8 43 0 0 0 0 0 8 0 8 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 8 8 8 8 0 8 0 0 0 % Q
% Arg: 0 0 0 15 15 0 0 0 0 8 8 8 0 0 8 % R
% Ser: 8 8 0 15 43 8 0 8 50 36 22 8 0 15 0 % S
% Thr: 8 0 0 0 8 0 8 43 8 8 0 0 22 0 0 % T
% Val: 36 8 0 0 0 8 36 0 8 0 0 0 8 15 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 15 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _