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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FBXL7 All Species: 13.64
Human Site: S220 Identified Species: 27.27
UniProt: Q9UJT9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UJT9 NP_036436.1 491 54575 S220 E L R R L E V S G C Y N I S N
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001087353 444 49825 N180 S G C Y N I S N E A V F D V V
Dog Lupus familis XP_546380 633 68780 A362 E L R R L E V A G C H N I S N
Cat Felis silvestris
Mouse Mus musculus Q5BJ29 491 54627 S220 E L R R L E V S G C Y N I S N
Rat Rattus norvegicus Q9QZH7 276 30442 R12 V N G V T K S R F E M F S N S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511052 486 54667 S215 E L R R L E V S G C Y N I S N
Chicken Gallus gallus XP_426048 491 54710 S220 E L R R L E V S G C Y N I S N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q2YDQ5 679 75714 Q314 R S S I S A L Q R E K L L L N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122429 442 49168 V178 F L S L T S L V L R H S R R V
Nematode Worm Caenorhab. elegans P34284 466 52046 N202 Y I G D G C P N L S Y L N I S
Sea Urchin Strong. purpuratus XP_001189280 543 60616 G271 L L H V E L M G C H Q I S N A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q708Y0 623 66043 D227 N L S D L T I D S C S G V G N
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 90.4 64.6 N.A. 98.3 21.5 N.A. 88.1 94.6 N.A. 21.9 N.A. N.A. 35.4 22.6 43.2
Protein Similarity: 100 N.A. 90.4 72.3 N.A. 98.9 38.2 N.A. 91.8 97.5 N.A. 35 N.A. N.A. 53.1 40.7 62.8
P-Site Identity: 100 N.A. 0 86.6 N.A. 100 0 N.A. 100 100 N.A. 6.6 N.A. N.A. 6.6 6.6 6.6
P-Site Similarity: 100 N.A. 6.6 100 N.A. 100 20 N.A. 100 100 N.A. 20 N.A. N.A. 26.6 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. 21.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 37.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 9 0 9 0 9 0 0 0 0 9 % A
% Cys: 0 0 9 0 0 9 0 0 9 50 0 0 0 0 0 % C
% Asp: 0 0 0 17 0 0 0 9 0 0 0 0 9 0 0 % D
% Glu: 42 0 0 0 9 42 0 0 9 17 0 0 0 0 0 % E
% Phe: 9 0 0 0 0 0 0 0 9 0 0 17 0 0 0 % F
% Gly: 0 9 17 0 9 0 0 9 42 0 0 9 0 9 0 % G
% His: 0 0 9 0 0 0 0 0 0 9 17 0 0 0 0 % H
% Ile: 0 9 0 9 0 9 9 0 0 0 0 9 42 9 0 % I
% Lys: 0 0 0 0 0 9 0 0 0 0 9 0 0 0 0 % K
% Leu: 9 67 0 9 50 9 17 0 17 0 0 17 9 9 0 % L
% Met: 0 0 0 0 0 0 9 0 0 0 9 0 0 0 0 % M
% Asn: 9 9 0 0 9 0 0 17 0 0 0 42 9 17 59 % N
% Pro: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 9 0 0 9 0 0 0 0 % Q
% Arg: 9 0 42 42 0 0 0 9 9 9 0 0 9 9 0 % R
% Ser: 9 9 25 0 9 9 17 34 9 9 9 9 17 42 17 % S
% Thr: 0 0 0 0 17 9 0 0 0 0 0 0 0 0 0 % T
% Val: 9 0 0 17 0 0 42 9 0 0 9 0 9 9 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 9 0 0 0 0 0 0 42 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _