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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LEF1 All Species: 22.73
Human Site: Y102 Identified Species: 55.56
UniProt: Q9UJU2 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UJU2 NP_001124185.1 399 44201 Y102 K H P D G G L Y N K G P S Y S
Chimpanzee Pan troglodytes XP_001136311 414 45726 Y102 K H P D G G L Y N K G P S Y S
Rhesus Macaque Macaca mulatta XP_001086645 399 44212 Y102 K H P D G G L Y N K G P S Y S
Dog Lupus familis XP_851241 400 44317 Y103 K H P D G G L Y N K G P S Y S
Cat Felis silvestris
Mouse Mus musculus P27782 397 44040 Y100 K H P D G G L Y N K G P S Y S
Rat Rattus norvegicus Q9QXN1 397 44005 Y100 K H P D G G L Y N K G P S Y S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510743 307 34255 G28 R E R W T G S G A V S E I S R
Chicken Gallus gallus NP_990344 369 40838 E90 D K G R E H P E E G K H P D G
Frog Xenopus laevis P70062 554 60282 G117 G G H Y L P N G A L S P S A R
Zebra Danio Brachydanio rerio Q9YHE8 560 61441 G121 T N P Y L S N G S L S P S T R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.1 99.7 98.5 N.A. 97.2 96.2 N.A. 60.1 87.4 43.1 44.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 94.9 99.7 99 N.A. 98.5 97.7 N.A. 66.4 89.4 53.7 55.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 6.6 0 13.3 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 13.3 0 13.3 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 20 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 60 0 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 0 10 0 0 10 0 0 10 10 0 0 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 10 10 0 60 70 0 30 0 10 60 0 0 0 10 % G
% His: 0 60 10 0 0 10 0 0 0 0 0 10 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % I
% Lys: 60 10 0 0 0 0 0 0 0 60 10 0 0 0 0 % K
% Leu: 0 0 0 0 20 0 60 0 0 20 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 0 20 0 60 0 0 0 0 0 0 % N
% Pro: 0 0 70 0 0 10 10 0 0 0 0 80 10 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 0 10 10 0 0 0 0 0 0 0 0 0 0 30 % R
% Ser: 0 0 0 0 0 10 10 0 10 0 30 0 80 10 60 % S
% Thr: 10 0 0 0 10 0 0 0 0 0 0 0 0 10 0 % T
% Val: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % V
% Trp: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 20 0 0 0 60 0 0 0 0 0 60 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _