Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX41 All Species: 17.27
Human Site: S23 Identified Species: 25.33
UniProt: Q9UJV9 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UJV9 NP_057306.2 622 69838 S23 V P A G G S R S E A E D E D D
Chimpanzee Pan troglodytes Q6GVM6 660 73172 S27 D L N S E K Q S G G A S R A S
Rhesus Macaque Macaca mulatta XP_001092587 622 69856 S23 V P A G G S R S E A E D E D D
Dog Lupus familis XP_536417 622 69897 S23 V T A T G S R S E T E D E D D
Cat Felis silvestris
Mouse Mus musculus Q91VN6 622 69759 S23 A T A G G S R S E D E D E D D
Rat Rattus norvegicus NP_001101516 622 69780 S23 A T A G G S R S E D E D E D D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425202 617 69207 E23 D G S D M S G E D D E D Y V P
Frog Xenopus laevis P24346 697 77284 S28 L N S A D A E S G V A G T K G
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3C0 619 69469 D23 E G D L D N E D Y V P Y V P V
Honey Bee Apis mellifera XP_392069 625 70130 P23 E E E K E S S P F D T D D N Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796437 603 68034 K23 Y V P Y V P L K E R R K Q K V
Poplar Tree Populus trichocarpa XP_002328711 587 65745 M23 R R A L T A Q M I L Q R R G N
Maize Zea mays NP_001147853 616 68366 V27 N Y E E Y I P V A K R R A M E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LU46 591 65788 K27 R R A I A A Q K I L Q R K G K
Baker's Yeast Sacchar. cerevisiae P24783 546 60981 N14 D Q Q Y N K T N Y K S R G G D
Red Bread Mold Neurospora crassa Q7SH33 1194 131283 D106 L D R L R S P D R R R D R S R
Conservation
Percent
Protein Identity: 100 28 99.6 99.1 N.A. 98.7 99 N.A. N.A. 92.5 30.2 N.A. N.A. 64.9 69.5 N.A. 68.8
Protein Similarity: 100 45.4 99.8 99.5 N.A. 98.8 99.1 N.A. N.A. 95.5 46.6 N.A. N.A. 79.9 82 N.A. 81.1
P-Site Identity: 100 6.6 100 80 N.A. 80 80 N.A. N.A. 20 6.6 N.A. N.A. 0 13.3 N.A. 6.6
P-Site Similarity: 100 13.3 100 80 N.A. 80 80 N.A. N.A. 33.3 26.6 N.A. N.A. 6.6 26.6 N.A. 13.3
Percent
Protein Identity: 58.2 55.9 N.A. 59.1 33.7 22.5
Protein Similarity: 73.4 73.7 N.A. 74.2 48.2 33.7
P-Site Identity: 6.6 0 N.A. 6.6 6.6 13.3
P-Site Similarity: 33.3 6.6 N.A. 33.3 13.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 44 7 7 19 0 0 7 13 13 0 7 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 19 7 7 7 13 0 0 13 7 25 0 50 7 32 38 % D
% Glu: 13 7 13 7 13 0 13 7 38 0 38 0 32 0 7 % E
% Phe: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % F
% Gly: 0 13 0 25 32 0 7 0 13 7 0 7 7 19 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 0 7 0 0 13 0 0 0 0 0 0 % I
% Lys: 0 0 0 7 0 13 0 13 0 13 0 7 7 13 7 % K
% Leu: 13 7 0 19 0 0 7 0 0 13 0 0 0 0 0 % L
% Met: 0 0 0 0 7 0 0 7 0 0 0 0 0 7 0 % M
% Asn: 7 7 7 0 7 7 0 7 0 0 0 0 0 7 7 % N
% Pro: 0 13 7 0 0 7 13 7 0 0 7 0 0 7 7 % P
% Gln: 0 7 7 0 0 0 19 0 0 0 13 0 7 0 0 % Q
% Arg: 13 13 7 0 7 0 32 0 7 13 19 25 19 0 7 % R
% Ser: 0 0 13 7 0 50 7 44 0 0 7 7 0 7 7 % S
% Thr: 0 19 0 7 7 0 7 0 0 7 7 0 7 0 0 % T
% Val: 19 7 0 0 7 0 0 7 0 13 0 0 7 7 13 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 7 0 13 7 0 0 0 13 0 0 7 7 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _