Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX41 All Species: 42.73
Human Site: S266 Identified Species: 62.67
UniProt: Q9UJV9 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UJV9 NP_057306.2 622 69838 S266 Y G L I I C P S R E L A R Q T
Chimpanzee Pan troglodytes Q6GVM6 660 73172 S267 R R K Q Y P I S L V L A P T R
Rhesus Macaque Macaca mulatta XP_001092587 622 69856 S266 Y G L I I C P S R E L A R Q T
Dog Lupus familis XP_536417 622 69897 S266 Y G L I I C P S R E L A R Q T
Cat Felis silvestris
Mouse Mus musculus Q91VN6 622 69759 S266 Y G L I I C P S R E L A R Q T
Rat Rattus norvegicus NP_001101516 622 69780 S266 Y G L I I C P S R E L A R Q T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425202 617 69207 S261 Y G L I I C P S R E L A R Q T
Frog Xenopus laevis P24346 697 77284 S310 R R K Q F P L S L V L A P T R
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3C0 619 69469 S262 Y G L I I C P S R E L A K Q T
Honey Bee Apis mellifera XP_392069 625 70130 S269 Y G L I I C P S R E L A K Q T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796437 603 68034 S247 Y G L I I C P S R E L A R Q T
Poplar Tree Populus trichocarpa XP_002328711 587 65745 M245 V E E F L I P M R A A G Y P E
Maize Zea mays NP_001147853 616 68366 S256 F G M I I C P S R E L A K Q T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LU46 591 65788 L249 V E Q F V A P L V E A G Y P P
Baker's Yeast Sacchar. cerevisiae P24783 546 60981 Q229 G G V P K S Q Q I R D L S R G
Red Bread Mold Neurospora crassa Q7SH33 1194 131283 R644 A L I M T P T R E L C T Q I Y
Conservation
Percent
Protein Identity: 100 28 99.6 99.1 N.A. 98.7 99 N.A. N.A. 92.5 30.2 N.A. N.A. 64.9 69.5 N.A. 68.8
Protein Similarity: 100 45.4 99.8 99.5 N.A. 98.8 99.1 N.A. N.A. 95.5 46.6 N.A. N.A. 79.9 82 N.A. 81.1
P-Site Identity: 100 20 100 100 N.A. 100 100 N.A. N.A. 100 20 N.A. N.A. 93.3 93.3 N.A. 100
P-Site Similarity: 100 20 100 100 N.A. 100 100 N.A. N.A. 100 20 N.A. N.A. 100 100 N.A. 100
Percent
Protein Identity: 58.2 55.9 N.A. 59.1 33.7 22.5
Protein Similarity: 73.4 73.7 N.A. 74.2 48.2 33.7
P-Site Identity: 13.3 80 N.A. 13.3 6.6 0
P-Site Similarity: 20 100 N.A. 20 20 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 0 7 0 0 0 7 13 75 0 0 0 % A
% Cys: 0 0 0 0 0 63 0 0 0 0 7 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % D
% Glu: 0 13 7 0 0 0 0 0 7 69 0 0 0 0 7 % E
% Phe: 7 0 0 13 7 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 7 69 0 0 0 0 0 0 0 0 0 13 0 0 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 7 63 63 7 7 0 7 0 0 0 0 7 0 % I
% Lys: 0 0 13 0 7 0 0 0 0 0 0 0 19 0 0 % K
% Leu: 0 7 57 0 7 0 7 7 13 7 75 7 0 0 0 % L
% Met: 0 0 7 7 0 0 0 7 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 7 0 19 75 0 0 0 0 0 13 13 7 % P
% Gln: 0 0 7 13 0 0 7 7 0 0 0 0 7 63 0 % Q
% Arg: 13 13 0 0 0 0 0 7 69 7 0 0 44 7 13 % R
% Ser: 0 0 0 0 0 7 0 75 0 0 0 0 7 0 0 % S
% Thr: 0 0 0 0 7 0 7 0 0 0 0 7 0 13 63 % T
% Val: 13 0 7 0 7 0 0 0 7 13 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 57 0 0 0 7 0 0 0 0 0 0 0 13 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _