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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX41
All Species:
20.3
Human Site:
S289
Identified Species:
29.78
UniProt:
Q9UJV9
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJV9
NP_057306.2
622
69838
S289
R
L
L
Q
E
D
S
S
P
L
L
R
C
A
L
Chimpanzee
Pan troglodytes
Q6GVM6
660
73172
R290
E
A
R
K
F
S
Y
R
S
R
V
R
P
C
V
Rhesus Macaque
Macaca mulatta
XP_001092587
622
69856
S289
R
L
L
Q
E
D
S
S
P
L
L
R
C
A
L
Dog
Lupus familis
XP_536417
622
69897
S289
R
L
L
Q
E
D
S
S
P
L
L
R
C
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q91VN6
622
69759
S289
R
L
L
Q
E
D
S
S
P
L
L
R
C
A
L
Rat
Rattus norvegicus
NP_001101516
622
69780
S289
R
L
L
Q
E
D
S
S
P
L
L
R
C
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425202
617
69207
L284
R
L
L
Q
E
D
S
L
P
P
L
R
C
A
L
Frog
Xenopus laevis
P24346
697
77284
R333
E
A
R
K
F
A
Y
R
S
R
V
R
P
C
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3C0
619
69469
M285
K
H
L
Q
A
C
G
M
P
E
I
R
S
C
L
Honey Bee
Apis mellifera
XP_392069
625
70130
C292
N
S
L
R
Q
A
G
C
P
E
I
R
S
C
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796437
603
68034
Q270
K
C
L
E
A
D
N
Q
P
T
L
R
S
M
L
Poplar Tree
Populus trichocarpa
XP_002328711
587
65745
L268
G
V
D
M
R
S
Q
L
E
V
V
K
K
G
V
Maize
Zea mays
NP_001147853
616
68366
Y279
I
P
L
K
E
A
G
Y
P
E
I
R
H
L
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LU46
591
65788
L272
G
I
D
M
R
S
Q
L
E
V
V
K
R
G
V
Baker's Yeast
Sacchar. cerevisiae
P24783
546
60981
E252
G
R
L
I
D
M
L
E
I
G
K
T
N
L
K
Red Bread Mold
Neurospora crassa
Q7SH33
1194
131283
A667
A
L
K
L
R
V
V
A
A
Y
G
G
N
A
I
Conservation
Percent
Protein Identity:
100
28
99.6
99.1
N.A.
98.7
99
N.A.
N.A.
92.5
30.2
N.A.
N.A.
64.9
69.5
N.A.
68.8
Protein Similarity:
100
45.4
99.8
99.5
N.A.
98.8
99.1
N.A.
N.A.
95.5
46.6
N.A.
N.A.
79.9
82
N.A.
81.1
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
N.A.
86.6
6.6
N.A.
N.A.
33.3
26.6
N.A.
40
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
N.A.
86.6
26.6
N.A.
N.A.
46.6
46.6
N.A.
60
Percent
Protein Identity:
58.2
55.9
N.A.
59.1
33.7
22.5
Protein Similarity:
73.4
73.7
N.A.
74.2
48.2
33.7
P-Site Identity:
0
33.3
N.A.
0
6.6
13.3
P-Site Similarity:
33.3
46.6
N.A.
33.3
13.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
13
0
0
13
19
0
7
7
0
0
0
0
44
0
% A
% Cys:
0
7
0
0
0
7
0
7
0
0
0
0
38
25
0
% C
% Asp:
0
0
13
0
7
44
0
0
0
0
0
0
0
0
0
% D
% Glu:
13
0
0
7
44
0
0
7
13
19
0
0
0
0
0
% E
% Phe:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
19
0
0
0
0
0
19
0
0
7
7
7
0
13
0
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
7
7
0
7
0
0
0
0
7
0
19
0
0
0
7
% I
% Lys:
13
0
7
19
0
0
0
0
0
0
7
13
7
0
7
% K
% Leu:
0
44
69
7
0
0
7
19
0
32
44
0
0
13
63
% L
% Met:
0
0
0
13
0
7
0
7
0
0
0
0
0
7
0
% M
% Asn:
7
0
0
0
0
0
7
0
0
0
0
0
13
0
0
% N
% Pro:
0
7
0
0
0
0
0
0
63
7
0
0
13
0
0
% P
% Gln:
0
0
0
44
7
0
13
7
0
0
0
0
0
0
0
% Q
% Arg:
38
7
13
7
19
0
0
13
0
13
0
75
7
0
0
% R
% Ser:
0
7
0
0
0
19
38
32
13
0
0
0
19
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% T
% Val:
0
7
0
0
0
7
7
0
0
13
25
0
0
0
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
13
7
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _