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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX41 All Species: 39.09
Human Site: S607 Identified Species: 57.33
UniProt: Q9UJV9 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UJV9 NP_057306.2 622 69838 S607 A M Q T K Q V S N I G R K D Y
Chimpanzee Pan troglodytes Q6GVM6 660 73172 S643 G Y G G F Y N S D G Y G G N Y
Rhesus Macaque Macaca mulatta XP_001092587 622 69856 S607 A M Q T K Q V S N I G R K D Y
Dog Lupus familis XP_536417 622 69897 S607 A M Q T K Q V S N I G R K D Y
Cat Felis silvestris
Mouse Mus musculus Q91VN6 622 69759 S607 A M Q T K Q V S N I G R K D Y
Rat Rattus norvegicus NP_001101516 622 69780 S607 A M Q T K Q V S N I G R K D Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425202 617 69207 S602 A M Q T K Q V S N I G R K D Y
Frog Xenopus laevis P24346 697 77284 S654 G A G S S F G S S R G G R S S
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3C0 619 69469 S604 A V Q N K Q A S N I G R R D Y
Honey Bee Apis mellifera XP_392069 625 70130 S610 A I Q N K Q A S N I G R R D Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796437 603 68034 S588 A M Q N K A A S S I G R R D Y
Poplar Tree Populus trichocarpa XP_002328711 587 65745 A571 H Q R S Q Q L A N S R R D Y F
Maize Zea mays NP_001147853 616 68366 A600 H Q K S M A I A G S R K D Y F
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LU46 591 65788 S575 H Q K S V A I S N S R K D Y F
Baker's Yeast Sacchar. cerevisiae P24783 546 60981 R532 R G G Y G G N R Q R D G G W G
Red Bread Mold Neurospora crassa Q7SH33 1194 131283 A1179 R E G T M A A A D A E S R A P
Conservation
Percent
Protein Identity: 100 28 99.6 99.1 N.A. 98.7 99 N.A. N.A. 92.5 30.2 N.A. N.A. 64.9 69.5 N.A. 68.8
Protein Similarity: 100 45.4 99.8 99.5 N.A. 98.8 99.1 N.A. N.A. 95.5 46.6 N.A. N.A. 79.9 82 N.A. 81.1
P-Site Identity: 100 13.3 100 100 N.A. 100 100 N.A. N.A. 100 13.3 N.A. N.A. 73.3 73.3 N.A. 66.6
P-Site Similarity: 100 26.6 100 100 N.A. 100 100 N.A. N.A. 100 33.3 N.A. N.A. 86.6 86.6 N.A. 80
Percent
Protein Identity: 58.2 55.9 N.A. 59.1 33.7 22.5
Protein Similarity: 73.4 73.7 N.A. 74.2 48.2 33.7
P-Site Identity: 20 0 N.A. 13.3 0 6.6
P-Site Similarity: 60 40 N.A. 46.6 0 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 57 7 0 0 0 25 25 19 0 7 0 0 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 13 0 7 0 19 57 0 % D
% Glu: 0 7 0 0 0 0 0 0 0 0 7 0 0 0 0 % E
% Phe: 0 0 0 0 7 7 0 0 0 0 0 0 0 0 19 % F
% Gly: 13 7 25 7 7 7 7 0 7 7 63 19 13 0 7 % G
% His: 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 0 0 0 13 0 0 57 0 0 0 0 0 % I
% Lys: 0 0 13 0 57 0 0 0 0 0 0 13 38 0 0 % K
% Leu: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % L
% Met: 0 44 0 0 13 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 19 0 0 13 0 63 0 0 0 0 7 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % P
% Gln: 0 19 57 0 7 57 0 0 7 0 0 0 0 0 0 % Q
% Arg: 13 0 7 0 0 0 0 7 0 13 19 63 32 0 0 % R
% Ser: 0 0 0 25 7 0 0 75 13 19 0 7 0 7 7 % S
% Thr: 0 0 0 44 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 7 0 0 7 0 38 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % W
% Tyr: 0 7 0 7 0 7 0 0 0 0 7 0 0 19 63 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _