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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX41 All Species: 22.42
Human Site: S68 Identified Species: 32.89
UniProt: Q9UJV9 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UJV9 NP_057306.2 622 69838 S68 E E Q Q D S G S E P R G D E D
Chimpanzee Pan troglodytes Q6GVM6 660 73172 W60 H D K D S S G W S C S K D K D
Rhesus Macaque Macaca mulatta XP_001092587 622 69856 S68 E E Q Q D S G S E P R G D E D
Dog Lupus familis XP_536417 622 69897 S68 E E Q Q D S G S E P R G D E D
Cat Felis silvestris
Mouse Mus musculus Q91VN6 622 69759 S68 E E Q Q D S G S E P R G D E D
Rat Rattus norvegicus NP_001101516 622 69780 S68 E E Q Q D S G S E P R G D E D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425202 617 69207 G63 E E Q R D S G G E Q R G D E D
Frog Xenopus laevis P24346 697 77284 R58 D S N W D S G R G G N G Y I N
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3C0 619 69469 D64 S S E N E N E D D S Q G A H D
Honey Bee Apis mellifera XP_392069 625 70130 K71 K S S S E N E K D D A D D D D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796437 603 68034 L58 Q Y L E E E E L D T G P R A N
Poplar Tree Populus trichocarpa XP_002328711 587 65745 S55 P S L L V K A S Q L K R D Q P
Maize Zea mays NP_001147853 616 68366 P60 S S L P M P P P P P L L P A Q
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LU46 591 65788 T59 P S L L V Q A T Q L K R D V P
Baker's Yeast Sacchar. cerevisiae P24783 546 60981 G44 P Q G G N Y R G G F G G R S N
Red Bread Mold Neurospora crassa Q7SH33 1194 131283 T206 E A K E A D V T A G L T R K L
Conservation
Percent
Protein Identity: 100 28 99.6 99.1 N.A. 98.7 99 N.A. N.A. 92.5 30.2 N.A. N.A. 64.9 69.5 N.A. 68.8
Protein Similarity: 100 45.4 99.8 99.5 N.A. 98.8 99.1 N.A. N.A. 95.5 46.6 N.A. N.A. 79.9 82 N.A. 81.1
P-Site Identity: 100 26.6 100 100 N.A. 100 100 N.A. N.A. 80 26.6 N.A. N.A. 13.3 13.3 N.A. 0
P-Site Similarity: 100 46.6 100 100 N.A. 100 100 N.A. N.A. 86.6 40 N.A. N.A. 46.6 46.6 N.A. 33.3
Percent
Protein Identity: 58.2 55.9 N.A. 59.1 33.7 22.5
Protein Similarity: 73.4 73.7 N.A. 74.2 48.2 33.7
P-Site Identity: 13.3 6.6 N.A. 6.6 6.6 6.6
P-Site Similarity: 33.3 6.6 N.A. 26.6 26.6 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 7 0 13 0 7 0 7 0 7 13 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % C
% Asp: 7 7 0 7 44 7 0 7 19 7 0 7 63 7 57 % D
% Glu: 44 38 7 13 19 7 19 0 38 0 0 0 0 38 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % F
% Gly: 0 0 7 7 0 0 50 13 13 13 13 57 0 0 0 % G
% His: 7 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % I
% Lys: 7 0 13 0 0 7 0 7 0 0 13 7 0 13 0 % K
% Leu: 0 0 25 13 0 0 0 7 0 13 13 7 0 0 7 % L
% Met: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 7 7 7 13 0 0 0 0 7 0 0 0 19 % N
% Pro: 19 0 0 7 0 7 7 7 7 38 0 7 7 0 13 % P
% Gln: 7 7 38 32 0 7 0 0 13 7 7 0 0 7 7 % Q
% Arg: 0 0 0 7 0 0 7 7 0 0 38 13 19 0 0 % R
% Ser: 13 38 7 7 7 50 0 38 7 7 7 0 0 7 0 % S
% Thr: 0 0 0 0 0 0 0 13 0 7 0 7 0 0 0 % T
% Val: 0 0 0 0 13 0 7 0 0 0 0 0 0 7 0 % V
% Trp: 0 0 0 7 0 0 0 7 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 0 7 0 0 0 0 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _