Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX41 All Species: 20
Human Site: T147 Identified Species: 29.33
UniProt: Q9UJV9 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UJV9 NP_057306.2 622 69838 T147 D P I K T S W T P P R Y V L S
Chimpanzee Pan troglodytes Q6GVM6 660 73172 L144 P L P P S E R L E Q E L F S G
Rhesus Macaque Macaca mulatta XP_001092587 622 69856 T147 D P I K T S W T P P R Y V L S
Dog Lupus familis XP_536417 622 69897 T147 D P I K T S W T P P R Y V L S
Cat Felis silvestris
Mouse Mus musculus Q91VN6 622 69759 T147 D P I K T S W T P P R Y V L S
Rat Rattus norvegicus NP_001101516 622 69780 T147 D P I K T S W T P P R Y V L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425202 617 69207 R142 D P I K T S W R A P R Y I L A
Frog Xenopus laevis P24346 697 77284 S168 D R G N S R W S D D R N D E D
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3C0 619 69469 K143 Q P I K T A W K P P R Y I R E
Honey Bee Apis mellifera XP_392069 625 70130 R150 E P I K T S W R P P R A A L T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796437 603 68034 T134 W K P P R C I T E L G E A R H
Poplar Tree Populus trichocarpa XP_002328711 587 65745 I131 I R K Q W H I I V D G E K I P
Maize Zea mays NP_001147853 616 68366 K137 E P I Q T G W K P P L R L R R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LU46 591 65788 I135 I R K Q W H I I V N G D D I P
Baker's Yeast Sacchar. cerevisiae P24783 546 60981 F120 T T F D E A G F P D Y V L N E
Red Bread Mold Neurospora crassa Q7SH33 1194 131283 E373 D D V A E D A E K D F D V L L
Conservation
Percent
Protein Identity: 100 28 99.6 99.1 N.A. 98.7 99 N.A. N.A. 92.5 30.2 N.A. N.A. 64.9 69.5 N.A. 68.8
Protein Similarity: 100 45.4 99.8 99.5 N.A. 98.8 99.1 N.A. N.A. 95.5 46.6 N.A. N.A. 79.9 82 N.A. 81.1
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. N.A. 73.3 20 N.A. N.A. 60 66.6 N.A. 6.6
P-Site Similarity: 100 6.6 100 100 N.A. 100 100 N.A. N.A. 86.6 33.3 N.A. N.A. 73.3 80 N.A. 6.6
Percent
Protein Identity: 58.2 55.9 N.A. 59.1 33.7 22.5
Protein Similarity: 73.4 73.7 N.A. 74.2 48.2 33.7
P-Site Identity: 0 40 N.A. 0 6.6 20
P-Site Similarity: 13.3 60 N.A. 13.3 20 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 0 13 7 0 7 0 0 7 13 0 7 % A
% Cys: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 50 7 0 7 0 7 0 0 7 25 0 13 13 0 7 % D
% Glu: 13 0 0 0 13 7 0 7 13 0 7 13 0 7 13 % E
% Phe: 0 0 7 0 0 0 0 7 0 0 7 0 7 0 0 % F
% Gly: 0 0 7 0 0 7 7 0 0 0 19 0 0 0 7 % G
% His: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 7 % H
% Ile: 13 0 57 0 0 0 19 13 0 0 0 0 13 13 0 % I
% Lys: 0 7 13 50 0 0 0 13 7 0 0 0 7 0 0 % K
% Leu: 0 7 0 0 0 0 0 7 0 7 7 7 13 50 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 0 0 0 0 0 7 0 7 0 7 0 % N
% Pro: 7 57 13 13 0 0 0 0 57 57 0 0 0 0 13 % P
% Gln: 7 0 0 19 0 0 0 0 0 7 0 0 0 0 0 % Q
% Arg: 0 19 0 0 7 7 7 13 0 0 57 7 0 19 7 % R
% Ser: 0 0 0 0 13 44 0 7 0 0 0 0 0 7 32 % S
% Thr: 7 7 0 0 57 0 0 38 0 0 0 0 0 0 7 % T
% Val: 0 0 7 0 0 0 0 0 13 0 0 7 38 0 0 % V
% Trp: 7 0 0 0 13 0 63 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 7 44 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _