Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX41 All Species: 34.24
Human Site: T603 Identified Species: 50.22
UniProt: Q9UJV9 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UJV9 NP_057306.2 622 69838 T603 P K L E A M Q T K Q V S N I G
Chimpanzee Pan troglodytes Q6GVM6 660 73172 G639 F G G G G Y G G F Y N S D G Y
Rhesus Macaque Macaca mulatta XP_001092587 622 69856 T603 P K L E A M Q T K Q V S N I G
Dog Lupus familis XP_536417 622 69897 T603 P K L E A M Q T K Q V S N I G
Cat Felis silvestris
Mouse Mus musculus Q91VN6 622 69759 T603 P K L E A M Q T K Q V S N I G
Rat Rattus norvegicus NP_001101516 622 69780 T603 P K L E A M Q T K Q V S N I G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425202 617 69207 T598 P K L E A M Q T K Q V S N I G
Frog Xenopus laevis P24346 697 77284 S650 R Q S S G A G S S F G S S R G
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3C0 619 69469 N600 P K L E A V Q N K Q A S N I G
Honey Bee Apis mellifera XP_392069 625 70130 N606 P K L E A I Q N K Q A S N I G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796437 603 68034 N584 P K L E A M Q N K A A S S I G
Poplar Tree Populus trichocarpa XP_002328711 587 65745 S567 P K L E H Q R S Q Q L A N S R
Maize Zea mays NP_001147853 616 68366 S596 P K L E H Q K S M A I A G S R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LU46 591 65788 S571 P K L E H Q K S V A I S N S R
Baker's Yeast Sacchar. cerevisiae P24783 546 60981 Y528 Y G G G R G G Y G G N R Q R D
Red Bread Mold Neurospora crassa Q7SH33 1194 131283 T1175 T R L L R E G T M A A A D A E
Conservation
Percent
Protein Identity: 100 28 99.6 99.1 N.A. 98.7 99 N.A. N.A. 92.5 30.2 N.A. N.A. 64.9 69.5 N.A. 68.8
Protein Similarity: 100 45.4 99.8 99.5 N.A. 98.8 99.1 N.A. N.A. 95.5 46.6 N.A. N.A. 79.9 82 N.A. 81.1
P-Site Identity: 100 6.6 100 100 N.A. 100 100 N.A. N.A. 100 13.3 N.A. N.A. 80 80 N.A. 73.3
P-Site Similarity: 100 13.3 100 100 N.A. 100 100 N.A. N.A. 100 33.3 N.A. N.A. 86.6 86.6 N.A. 80
Percent
Protein Identity: 58.2 55.9 N.A. 59.1 33.7 22.5
Protein Similarity: 73.4 73.7 N.A. 74.2 48.2 33.7
P-Site Identity: 40 26.6 N.A. 40 0 13.3
P-Site Similarity: 73.3 53.3 N.A. 60 0 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 57 7 0 0 0 25 25 19 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 7 % D
% Glu: 0 0 0 75 0 7 0 0 0 0 0 0 0 0 7 % E
% Phe: 7 0 0 0 0 0 0 0 7 7 0 0 0 0 0 % F
% Gly: 0 13 13 13 13 7 25 7 7 7 7 0 7 7 63 % G
% His: 0 0 0 0 19 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 7 0 0 0 0 13 0 0 57 0 % I
% Lys: 0 75 0 0 0 0 13 0 57 0 0 0 0 0 0 % K
% Leu: 0 0 82 7 0 0 0 0 0 0 7 0 0 0 0 % L
% Met: 0 0 0 0 0 44 0 0 13 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 19 0 0 13 0 63 0 0 % N
% Pro: 75 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 7 0 0 0 19 57 0 7 57 0 0 7 0 0 % Q
% Arg: 7 7 0 0 13 0 7 0 0 0 0 7 0 13 19 % R
% Ser: 0 0 7 7 0 0 0 25 7 0 0 75 13 19 0 % S
% Thr: 7 0 0 0 0 0 0 44 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 7 0 0 7 0 38 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 7 0 7 0 7 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _