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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX41
All Species:
36.36
Human Site:
Y138
Identified Species:
53.33
UniProt:
Q9UJV9
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJV9
NP_057306.2
622
69838
Y138
E
M
A
K
G
I
T
Y
D
D
P
I
K
T
S
Chimpanzee
Pan troglodytes
Q6GVM6
660
73172
S135
K
S
D
E
D
D
W
S
K
P
L
P
P
S
E
Rhesus Macaque
Macaca mulatta
XP_001092587
622
69856
Y138
E
M
A
K
G
I
T
Y
D
D
P
I
K
T
S
Dog
Lupus familis
XP_536417
622
69897
Y138
E
M
A
K
G
I
T
Y
D
D
P
I
K
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q91VN6
622
69759
Y138
E
M
A
K
G
I
T
Y
D
D
P
I
K
T
S
Rat
Rattus norvegicus
NP_001101516
622
69780
Y138
E
M
A
K
G
I
T
Y
D
D
P
I
K
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425202
617
69207
Y133
E
M
A
K
G
I
T
Y
D
D
P
I
K
T
S
Frog
Xenopus laevis
P24346
697
77284
R159
S
D
K
S
G
F
G
R
F
D
R
G
N
S
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3C0
619
69469
Y134
E
L
A
K
G
I
Q
Y
E
Q
P
I
K
T
A
Honey Bee
Apis mellifera
XP_392069
625
70130
Y141
E
L
A
K
G
I
Q
Y
E
E
P
I
K
T
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796437
603
68034
T125
I
Y
S
E
S
L
V
T
G
W
K
P
P
R
C
Poplar Tree
Populus trichocarpa
XP_002328711
587
65745
D122
K
M
S
R
K
E
C
D
A
I
R
K
Q
W
H
Maize
Zea mays
NP_001147853
616
68366
Y128
E
I
A
K
G
I
I
Y
T
E
P
I
Q
T
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LU46
591
65788
D126
K
M
S
S
K
Q
R
D
L
I
R
K
Q
W
H
Baker's Yeast
Sacchar. cerevisiae
P24783
546
60981
P111
S
G
H
D
I
P
K
P
I
T
T
F
D
E
A
Red Bread Mold
Neurospora crassa
Q7SH33
1194
131283
A364
N
A
D
D
T
P
Y
A
D
D
D
V
A
E
D
Conservation
Percent
Protein Identity:
100
28
99.6
99.1
N.A.
98.7
99
N.A.
N.A.
92.5
30.2
N.A.
N.A.
64.9
69.5
N.A.
68.8
Protein Similarity:
100
45.4
99.8
99.5
N.A.
98.8
99.1
N.A.
N.A.
95.5
46.6
N.A.
N.A.
79.9
82
N.A.
81.1
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
N.A.
100
13.3
N.A.
N.A.
66.6
73.3
N.A.
0
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
N.A.
100
20
N.A.
N.A.
86.6
93.3
N.A.
20
Percent
Protein Identity:
58.2
55.9
N.A.
59.1
33.7
22.5
Protein Similarity:
73.4
73.7
N.A.
74.2
48.2
33.7
P-Site Identity:
6.6
60
N.A.
6.6
0
13.3
P-Site Similarity:
33.3
80
N.A.
26.6
6.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
57
0
0
0
0
7
7
0
0
0
7
0
13
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
7
% C
% Asp:
0
7
13
13
7
7
0
13
44
50
7
0
7
0
7
% D
% Glu:
57
0
0
13
0
7
0
0
13
13
0
0
0
13
7
% E
% Phe:
0
0
0
0
0
7
0
0
7
0
0
7
0
0
0
% F
% Gly:
0
7
0
0
63
0
7
0
7
0
0
7
0
0
7
% G
% His:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
13
% H
% Ile:
7
7
0
0
7
57
7
0
7
13
0
57
0
0
0
% I
% Lys:
19
0
7
57
13
0
7
0
7
0
7
13
50
0
0
% K
% Leu:
0
13
0
0
0
7
0
0
7
0
7
0
0
0
0
% L
% Met:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% N
% Pro:
0
0
0
0
0
13
0
7
0
7
57
13
13
0
0
% P
% Gln:
0
0
0
0
0
7
13
0
0
7
0
0
19
0
0
% Q
% Arg:
0
0
0
7
0
0
7
7
0
0
19
0
0
7
7
% R
% Ser:
13
7
19
13
7
0
0
7
0
0
0
0
0
13
44
% S
% Thr:
0
0
0
0
7
0
38
7
7
7
7
0
0
57
0
% T
% Val:
0
0
0
0
0
0
7
0
0
0
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
7
0
0
7
0
0
0
13
0
% W
% Tyr:
0
7
0
0
0
0
7
57
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _