Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX41 All Species: 19.39
Human Site: Y36 Identified Species: 28.44
UniProt: Q9UJV9 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UJV9 NP_057306.2 622 69838 Y36 D D E D Y V P Y V P L R Q R R
Chimpanzee Pan troglodytes Q6GVM6 660 73172 P40 A S K G R Y I P P H L R N R E
Rhesus Macaque Macaca mulatta XP_001092587 622 69856 Y36 D D E D Y V P Y V P L R Q R R
Dog Lupus familis XP_536417 622 69897 Y36 D D E E Y V P Y V P L R Q R R
Cat Felis silvestris
Mouse Mus musculus Q91VN6 622 69759 Y36 D D E D Y V P Y V P L R Q R R
Rat Rattus norvegicus NP_001101516 622 69780 Y36 D D E D Y V P Y V P L R Q R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425202 617 69207 Q36 V P Y V P V K Q R K Q Q M L Q
Frog Xenopus laevis P24346 697 77284 H41 K G R Y I P P H L R N K E A S
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3C0 619 69469 Q36 P V K E R K K Q H M I K L G R
Honey Bee Apis mellifera XP_392069 625 70130 V36 N Y I P Y V P V K E R K K Q Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796437 603 68034 I36 K V D R I Q K I V T R R V V E
Poplar Tree Populus trichocarpa XP_002328711 587 65745 D36 G N I S A L E D E L E K S K L
Maize Zea mays NP_001147853 616 68366 Q40 M E A E R L R Q L R L S K S A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LU46 591 65788 E40 G K A S E L E E E A D K E K L
Baker's Yeast Sacchar. cerevisiae P24783 546 60981 N27 G D F R G G R N S D R N S Y N
Red Bread Mold Neurospora crassa Q7SH33 1194 131283 Y119 S R D P D R E Y R P R R D D S
Conservation
Percent
Protein Identity: 100 28 99.6 99.1 N.A. 98.7 99 N.A. N.A. 92.5 30.2 N.A. N.A. 64.9 69.5 N.A. 68.8
Protein Similarity: 100 45.4 99.8 99.5 N.A. 98.8 99.1 N.A. N.A. 95.5 46.6 N.A. N.A. 79.9 82 N.A. 81.1
P-Site Identity: 100 20 100 93.3 N.A. 100 100 N.A. N.A. 6.6 6.6 N.A. N.A. 6.6 20 N.A. 13.3
P-Site Similarity: 100 26.6 100 100 N.A. 100 100 N.A. N.A. 20 33.3 N.A. N.A. 33.3 53.3 N.A. 20
Percent
Protein Identity: 58.2 55.9 N.A. 59.1 33.7 22.5
Protein Similarity: 73.4 73.7 N.A. 74.2 48.2 33.7
P-Site Identity: 0 6.6 N.A. 0 6.6 20
P-Site Similarity: 26.6 40 N.A. 26.6 6.6 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 13 0 7 0 0 0 0 7 0 0 0 7 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 32 38 13 25 7 0 0 7 0 7 7 0 7 7 0 % D
% Glu: 0 7 32 19 7 0 19 7 13 7 7 0 13 0 13 % E
% Phe: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 19 7 0 7 7 7 0 0 0 0 0 0 0 7 0 % G
% His: 0 0 0 0 0 0 0 7 7 7 0 0 0 0 0 % H
% Ile: 0 0 13 0 13 0 7 7 0 0 7 0 0 0 0 % I
% Lys: 13 7 13 0 0 7 19 0 7 7 0 32 13 13 0 % K
% Leu: 0 0 0 0 0 19 0 0 13 7 44 0 7 7 13 % L
% Met: 7 0 0 0 0 0 0 0 0 7 0 0 7 0 0 % M
% Asn: 7 7 0 0 0 0 0 7 0 0 7 7 7 0 7 % N
% Pro: 7 7 0 13 7 7 44 7 7 38 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 7 0 19 0 0 7 7 32 7 13 % Q
% Arg: 0 7 7 13 19 7 13 0 13 13 25 50 0 38 38 % R
% Ser: 7 7 0 13 0 0 0 0 7 0 0 7 13 7 13 % S
% Thr: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % T
% Val: 7 13 0 7 0 44 0 7 38 0 0 0 7 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 7 7 38 7 0 38 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _