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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX41 All Species: 37.88
Human Site: Y614 Identified Species: 55.56
UniProt: Q9UJV9 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UJV9 NP_057306.2 622 69838 Y614 S N I G R K D Y L A H S S M D
Chimpanzee Pan troglodytes Q6GVM6 660 73172 Y650 S D G Y G G N Y N S Q G V D W
Rhesus Macaque Macaca mulatta XP_001092587 622 69856 Y614 S N I G R K D Y L A H S S M D
Dog Lupus familis XP_536417 622 69897 Y614 S N I G R K D Y L A H S S M D
Cat Felis silvestris
Mouse Mus musculus Q91VN6 622 69759 Y614 S N I G R K D Y L A H S S M D
Rat Rattus norvegicus NP_001101516 622 69780 Y614 S N I G R K D Y L A H S S M D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425202 617 69207 Y609 S N I G R K D Y L A H S S M D
Frog Xenopus laevis P24346 697 77284 S661 S S R G G R S S G H G G S R G
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3C0 619 69469 Y611 S N I G R R D Y L S N T A A D
Honey Bee Apis mellifera XP_392069 625 70130 Y617 S N I G R R D Y L A S N A A D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796437 603 68034 Y595 S S I G R R D Y L A H G A A D
Poplar Tree Populus trichocarpa XP_002328711 587 65745 F578 A N S R R D Y F G S G G Y R G
Maize Zea mays NP_001147853 616 68366 F607 A G S R K D Y F G G G G Y R G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LU46 591 65788 F582 S N S R K D Y F G S G G Y R G
Baker's Yeast Sacchar. cerevisiae P24783 546 60981 G539 R Q R D G G W G N R G R S N Y
Red Bread Mold Neurospora crassa Q7SH33 1194 131283 P1186 A D A E S R A P A S G R Y T I
Conservation
Percent
Protein Identity: 100 28 99.6 99.1 N.A. 98.7 99 N.A. N.A. 92.5 30.2 N.A. N.A. 64.9 69.5 N.A. 68.8
Protein Similarity: 100 45.4 99.8 99.5 N.A. 98.8 99.1 N.A. N.A. 95.5 46.6 N.A. N.A. 79.9 82 N.A. 81.1
P-Site Identity: 100 13.3 100 100 N.A. 100 100 N.A. N.A. 100 20 N.A. N.A. 60 66.6 N.A. 66.6
P-Site Similarity: 100 33.3 100 100 N.A. 100 100 N.A. N.A. 100 33.3 N.A. N.A. 93.3 86.6 N.A. 86.6
Percent
Protein Identity: 58.2 55.9 N.A. 59.1 33.7 22.5
Protein Similarity: 73.4 73.7 N.A. 74.2 48.2 33.7
P-Site Identity: 13.3 0 N.A. 13.3 6.6 0
P-Site Similarity: 33.3 20 N.A. 33.3 6.6 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 0 7 0 0 0 7 0 7 50 0 0 19 19 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 13 0 7 0 19 57 0 0 0 0 0 0 7 57 % D
% Glu: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 19 0 0 0 0 0 0 0 % F
% Gly: 0 7 7 63 19 13 0 7 25 7 38 38 0 0 25 % G
% His: 0 0 0 0 0 0 0 0 0 7 44 0 0 0 0 % H
% Ile: 0 0 57 0 0 0 0 0 0 0 0 0 0 0 7 % I
% Lys: 0 0 0 0 13 38 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 57 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 38 0 % M
% Asn: 0 63 0 0 0 0 7 0 13 0 7 7 0 7 0 % N
% Pro: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % P
% Gln: 0 7 0 0 0 0 0 0 0 0 7 0 0 0 0 % Q
% Arg: 7 0 13 19 63 32 0 0 0 7 0 13 0 25 0 % R
% Ser: 75 13 19 0 7 0 7 7 0 32 7 38 50 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 7 0 7 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 7 % W
% Tyr: 0 0 0 7 0 0 19 63 0 0 0 0 25 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _