KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DNMT3L
All Species:
13.64
Human Site:
T63
Identified Species:
50
UniProt:
Q9UJW3
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJW3
NP_037501.2
387
43670
T63
C
G
S
L
Q
V
H
T
Q
H
P
L
F
E
G
Chimpanzee
Pan troglodytes
XP_525483
387
43705
T63
C
G
S
L
Q
V
H
T
Q
H
P
L
F
E
G
Rhesus Macaque
Macaca mulatta
XP_001118368
418
47437
T94
C
G
S
L
Q
V
H
T
Q
H
P
L
F
E
G
Dog
Lupus familis
XP_849972
336
38155
L30
A
P
C
K
D
K
F
L
D
C
L
F
L
Y
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWR8
421
47974
T97
C
G
T
L
Q
V
Y
T
R
H
P
L
F
E
G
Rat
Rattus norvegicus
Q1LZ50
422
48260
A98
C
G
S
L
Q
V
Y
A
Q
H
P
L
F
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q4W5Z4
877
98926
L469
C
G
S
L
N
V
T
L
E
H
P
L
F
I
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
86.3
65.6
N.A.
58.1
59.7
N.A.
N.A.
21.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
88.5
74.9
N.A.
72.9
73.6
N.A.
N.A.
29.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
80
86.6
N.A.
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
0
N.A.
100
93.3
N.A.
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% A
% Cys:
86
0
15
0
0
0
0
0
0
15
0
0
0
0
0
% C
% Asp:
0
0
0
0
15
0
0
0
15
0
0
0
0
0
15
% D
% Glu:
0
0
0
0
0
0
0
0
15
0
0
0
0
72
0
% E
% Phe:
0
0
0
0
0
0
15
0
0
0
0
15
86
0
0
% F
% Gly:
0
86
0
0
0
0
0
0
0
0
0
0
0
0
86
% G
% His:
0
0
0
0
0
0
43
0
0
86
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% I
% Lys:
0
0
0
15
0
15
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
86
0
0
0
29
0
0
15
86
15
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
15
0
0
0
0
0
0
0
0
86
0
0
0
0
% P
% Gln:
0
0
0
0
72
0
0
0
58
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% R
% Ser:
0
0
72
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
15
0
0
0
15
58
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
86
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
29
0
0
0
0
0
0
15
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _