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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDC23 All Species: 25.45
Human Site: S159 Identified Species: 40
UniProt: Q9UJX2 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UJX2 NP_004652.2 597 68834 S159 R E L R V E L S K K H Q A R E
Chimpanzee Pan troglodytes XP_517953 597 68798 S159 R E L R V E L S K K H Q A R E
Rhesus Macaque Macaca mulatta XP_001112573 597 68791 S159 R E L R V E L S K K H Q A R E
Dog Lupus familis XP_538647 597 68772 S159 R E L R V E L S K K H Q A R E
Cat Felis silvestris
Mouse Mus musculus Q8BGZ4 597 68543 S159 R E L R V E L S R K H Q A R G
Rat Rattus norvegicus NP_001094129 597 68604 S159 R E L R V E L S R K H Q A R G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001079890 580 67402 D150 K H K A R E L D G F G L Y L Y
Zebra Danio Brachydanio rerio NP_957227 579 66924 D151 K H S A G E L D G F A L Y L Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610036 678 77547 S152 L R M E Y G K S R L D G Y G I
Honey Bee Apis mellifera XP_396943 575 67150 L151 L D G F G L Y L F G V T L K K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782099 467 54518 L50 S A K W C A E L S Y S L Q N V
Poplar Tree Populus trichocarpa XP_002318627 576 67353 V159 D A V N R E L V S L E R E L S
Maize Zea mays NP_001147126 599 68030 E156 Y A L Y M A G E K R K E A E M
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_190398 579 67116 V161 D A I N R E L V S L E R D L S
Baker's Yeast Sacchar. cerevisiae P16522 626 73096 S178 R A N L K M V S N E H E S Q S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.1 98.6 N.A. 95.3 95.6 N.A. N.A. N.A. 86.7 77.8 N.A. 40.1 51.7 N.A. 47.7
Protein Similarity: 100 100 99.5 99.5 N.A. 97.4 97.6 N.A. N.A. N.A. 91.7 86.7 N.A. 55.4 68.5 N.A. 60.6
P-Site Identity: 100 100 100 100 N.A. 86.6 86.6 N.A. N.A. N.A. 13.3 13.3 N.A. 6.6 0 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. N.A. N.A. 20 20 N.A. 20 20 N.A. 0
Percent
Protein Identity: 40.3 41.2 N.A. 41.7 29.3 N.A.
Protein Similarity: 57.7 57.9 N.A. 57.4 48.4 N.A.
P-Site Identity: 13.3 20 N.A. 13.3 20 N.A.
P-Site Similarity: 26.6 40 N.A. 26.6 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 34 0 14 0 14 0 0 0 0 7 0 47 0 0 % A
% Cys: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 14 7 0 0 0 0 0 14 0 0 7 0 7 0 0 % D
% Glu: 0 40 0 7 0 67 7 7 0 7 14 14 7 7 27 % E
% Phe: 0 0 0 7 0 0 0 0 7 14 0 0 0 0 0 % F
% Gly: 0 0 7 0 14 7 7 0 14 7 7 7 0 7 14 % G
% His: 0 14 0 0 0 0 0 0 0 0 47 0 0 0 0 % H
% Ile: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 7 % I
% Lys: 14 0 14 0 7 0 7 0 34 40 7 0 0 7 7 % K
% Leu: 14 0 47 7 0 7 67 14 0 20 0 20 7 27 0 % L
% Met: 0 0 7 0 7 7 0 0 0 0 0 0 0 0 7 % M
% Asn: 0 0 7 14 0 0 0 0 7 0 0 0 0 7 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 40 7 7 0 % Q
% Arg: 47 7 0 40 20 0 0 0 20 7 0 14 0 40 0 % R
% Ser: 7 0 7 0 0 0 0 54 20 0 7 0 7 0 20 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % T
% Val: 0 0 7 0 40 0 7 14 0 0 7 0 0 0 7 % V
% Trp: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 7 7 0 7 0 0 7 0 0 20 0 14 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _