KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC23
All Species:
35.15
Human Site:
Y422
Identified Species:
55.24
UniProt:
Q9UJX2
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJX2
NP_004652.2
597
68834
Y422
P
F
Y
C
L
Y
Y
Y
R
R
A
H
Q
L
R
Chimpanzee
Pan troglodytes
XP_517953
597
68798
Y422
P
F
Y
C
L
Y
Y
Y
R
R
A
H
Q
L
R
Rhesus Macaque
Macaca mulatta
XP_001112573
597
68791
Y422
P
F
Y
C
L
Y
Y
Y
R
R
A
H
Q
L
R
Dog
Lupus familis
XP_538647
597
68772
Y422
P
F
Y
C
L
Y
Y
Y
R
R
A
H
Q
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGZ4
597
68543
Y422
P
F
Y
C
L
Y
Y
Y
R
R
A
H
Q
L
R
Rat
Rattus norvegicus
NP_001094129
597
68604
Y422
P
F
Y
C
L
Y
Y
Y
R
R
A
H
Q
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079890
580
67402
Y404
P
F
Y
C
L
Y
Y
Y
R
R
A
H
Q
L
R
Zebra Danio
Brachydanio rerio
NP_957227
579
66924
Y405
P
F
Y
S
L
Y
Y
Y
R
K
A
H
Q
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610036
678
77547
F409
H
Y
Y
S
L
Y
Y
F
K
I
A
H
Q
L
R
Honey Bee
Apis mellifera
XP_396943
575
67150
R406
Y
K
Q
A
Q
L
L
R
P
H
D
S
R
M
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782099
467
54518
M304
N
L
L
Y
V
K
E
M
K
A
E
L
S
H
L
Poplar Tree
Populus trichocarpa
XP_002318627
576
67353
Q413
R
A
W
Y
G
L
G
Q
A
Y
E
M
M
G
M
Maize
Zea mays
NP_001147126
599
68030
Y416
S
P
A
A
I
D
A
Y
R
R
A
V
D
I
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_190398
579
67116
Q415
R
A
W
Y
G
L
G
Q
A
Y
E
M
M
G
M
Baker's Yeast
Sacchar. cerevisiae
P16522
626
73096
Y454
S
H
A
A
I
E
C
Y
R
R
A
V
D
I
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.1
98.6
N.A.
95.3
95.6
N.A.
N.A.
N.A.
86.7
77.8
N.A.
40.1
51.7
N.A.
47.7
Protein Similarity:
100
100
99.5
99.5
N.A.
97.4
97.6
N.A.
N.A.
N.A.
91.7
86.7
N.A.
55.4
68.5
N.A.
60.6
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
N.A.
100
86.6
N.A.
60
0
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
N.A.
100
93.3
N.A.
80
13.3
N.A.
13.3
Percent
Protein Identity:
40.3
41.2
N.A.
41.7
29.3
N.A.
Protein Similarity:
57.7
57.9
N.A.
57.4
48.4
N.A.
P-Site Identity:
0
26.6
N.A.
0
26.6
N.A.
P-Site Similarity:
6.6
40
N.A.
6.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
14
20
0
0
7
0
14
7
74
0
0
0
0
% A
% Cys:
0
0
0
47
0
0
7
0
0
0
0
0
0
0
7
% C
% Asp:
0
0
0
0
0
7
0
0
0
0
7
0
14
0
0
% D
% Glu:
0
0
0
0
0
7
7
0
0
0
20
0
0
0
0
% E
% Phe:
0
54
0
0
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
14
0
14
0
0
0
0
0
0
14
0
% G
% His:
7
7
0
0
0
0
0
0
0
7
0
60
0
7
0
% H
% Ile:
0
0
0
0
14
0
0
0
0
7
0
0
0
14
0
% I
% Lys:
0
7
0
0
0
7
0
0
14
7
0
0
0
0
0
% K
% Leu:
0
7
7
0
60
20
7
0
0
0
0
7
0
60
7
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
14
14
7
14
% M
% Asn:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% N
% Pro:
54
7
0
0
0
0
0
0
7
0
0
0
0
0
0
% P
% Gln:
0
0
7
0
7
0
0
14
0
0
0
0
60
0
0
% Q
% Arg:
14
0
0
0
0
0
0
7
67
60
0
0
7
0
60
% R
% Ser:
14
0
0
14
0
0
0
0
0
0
0
7
7
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
7
0
0
0
0
0
0
14
0
0
7
% V
% Trp:
0
0
14
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
7
60
20
0
60
60
67
0
14
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _