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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDC23 All Species: 33.94
Human Site: Y519 Identified Species: 53.33
UniProt: Q9UJX2 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UJX2 NP_004652.2 597 68834 Y519 A F R Y L A Q Y Y F K C K L W
Chimpanzee Pan troglodytes XP_517953 597 68798 Y519 A F R Y L A Q Y Y F K C K L W
Rhesus Macaque Macaca mulatta XP_001112573 597 68791 Y519 A F R Y L A Q Y Y F K C K L W
Dog Lupus familis XP_538647 597 68772 Y519 A F R Y L A Q Y Y F K C K L W
Cat Felis silvestris
Mouse Mus musculus Q8BGZ4 597 68543 Y519 A F R Y L A Q Y Y F K C K L W
Rat Rattus norvegicus NP_001094129 597 68604 Y519 A F R Y L A Q Y Y F K C K L W
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001079890 580 67402 Y501 A F R Y L A Q Y Y F K C K L W
Zebra Danio Brachydanio rerio NP_957227 579 66924 Y502 A L R Y L G Q Y Y F K N K L Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610036 678 77547 Y503 G F I T L A N Y Y E K K G E Y
Honey Bee Apis mellifera XP_396943 575 67150 Q499 Q Y H L K R E Q L D Y A N H Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782099 467 54518 Y395 K R D F R A W Y G L G Q T Y D
Poplar Tree Populus trichocarpa XP_002318627 576 67353 R504 Y Y K K D L D R M E D E E R E
Maize Zea mays NP_001147126 599 68030 E515 G M L G Q S E E A A F Y Y K K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_190398 579 67116 R506 Y F E K D L E R M D A E G L E
Baker's Yeast Sacchar. cerevisiae P16522 626 73096 D551 Q L Y E E L E D L Q E C K K F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.1 98.6 N.A. 95.3 95.6 N.A. N.A. N.A. 86.7 77.8 N.A. 40.1 51.7 N.A. 47.7
Protein Similarity: 100 100 99.5 99.5 N.A. 97.4 97.6 N.A. N.A. N.A. 91.7 86.7 N.A. 55.4 68.5 N.A. 60.6
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 100 73.3 N.A. 40 0 N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 100 80 N.A. 46.6 20 N.A. 20
Percent
Protein Identity: 40.3 41.2 N.A. 41.7 29.3 N.A.
Protein Similarity: 57.7 57.9 N.A. 57.4 48.4 N.A.
P-Site Identity: 0 0 N.A. 13.3 13.3 N.A.
P-Site Similarity: 20 13.3 N.A. 20 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 54 0 0 0 0 60 0 0 7 7 7 7 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 54 0 0 0 % C
% Asp: 0 0 7 0 14 0 7 7 0 14 7 0 0 0 7 % D
% Glu: 0 0 7 7 7 0 27 7 0 14 7 14 7 7 14 % E
% Phe: 0 60 0 7 0 0 0 0 0 54 7 0 0 0 7 % F
% Gly: 14 0 0 7 0 7 0 0 7 0 7 0 14 0 0 % G
% His: 0 0 7 0 0 0 0 0 0 0 0 0 0 7 0 % H
% Ile: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 7 0 7 14 7 0 0 0 0 0 60 7 60 14 7 % K
% Leu: 0 14 7 7 60 20 0 0 14 7 0 0 0 60 0 % L
% Met: 0 7 0 0 0 0 0 0 14 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 7 0 0 0 0 7 7 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 14 0 0 0 7 0 54 7 0 7 0 7 0 0 0 % Q
% Arg: 0 7 54 0 7 7 0 14 0 0 0 0 0 7 0 % R
% Ser: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 7 0 0 0 0 0 0 0 0 7 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 47 % W
% Tyr: 14 14 7 54 0 0 0 67 60 0 7 7 7 7 20 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _