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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDC23 All Species: 31.82
Human Site: Y99 Identified Species: 50
UniProt: Q9UJX2 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UJX2 NP_004652.2 597 68834 Y99 A Y F D V K E Y D R A A H F L
Chimpanzee Pan troglodytes XP_517953 597 68798 Y99 A Y F D V K E Y D R A A H F L
Rhesus Macaque Macaca mulatta XP_001112573 597 68791 Y99 A Y F D V K E Y D R A A H F L
Dog Lupus familis XP_538647 597 68772 Y99 A Y F D V K E Y D R A A H F L
Cat Felis silvestris
Mouse Mus musculus Q8BGZ4 597 68543 Y99 A Y F D V K E Y D R A A H F L
Rat Rattus norvegicus NP_001094129 597 68604 Y99 A Y F D V K E Y D R A A H F L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001079890 580 67402 Y97 G C K S Q K A Y F M Y M Y S R
Zebra Danio Brachydanio rerio NP_957227 579 66924 Y98 G C R S Q K A Y F L Y M Y S R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610036 678 77547 E99 A H A V R N C E S S V P R F L
Honey Bee Apis mellifera XP_396943 575 67150 L98 K T P K V R F L H L Y S R Y L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782099 467 54518
Poplar Tree Populus trichocarpa XP_002318627 576 67353 Y106 S Y F D C R E Y K R A A H V L
Maize Zea mays NP_001147126 599 68030 V99 P L G G V S Y V S T P I P D D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_190398 579 67116 Y108 S Y F D C R E Y R R A S H M L
Baker's Yeast Sacchar. cerevisiae P16522 626 73096 F101 T L F D A K E F D R C V F F L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.1 98.6 N.A. 95.3 95.6 N.A. N.A. N.A. 86.7 77.8 N.A. 40.1 51.7 N.A. 47.7
Protein Similarity: 100 100 99.5 99.5 N.A. 97.4 97.6 N.A. N.A. N.A. 91.7 86.7 N.A. 55.4 68.5 N.A. 60.6
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 13.3 13.3 N.A. 20 13.3 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 20 20 N.A. 26.6 33.3 N.A. 0
Percent
Protein Identity: 40.3 41.2 N.A. 41.7 29.3 N.A.
Protein Similarity: 57.7 57.9 N.A. 57.4 48.4 N.A.
P-Site Identity: 66.6 6.6 N.A. 60 53.3 N.A.
P-Site Similarity: 80 6.6 N.A. 80 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 47 0 7 0 7 0 14 0 0 0 54 47 0 0 0 % A
% Cys: 0 14 0 0 14 0 7 0 0 0 7 0 0 0 0 % C
% Asp: 0 0 0 60 0 0 0 0 47 0 0 0 0 7 7 % D
% Glu: 0 0 0 0 0 0 60 7 0 0 0 0 0 0 0 % E
% Phe: 0 0 60 0 0 0 7 7 14 0 0 0 7 54 0 % F
% Gly: 14 0 7 7 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 7 0 0 0 0 0 0 7 0 0 0 54 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % I
% Lys: 7 0 7 7 0 60 0 0 7 0 0 0 0 0 0 % K
% Leu: 0 14 0 0 0 0 0 7 0 14 0 0 0 0 74 % L
% Met: 0 0 0 0 0 0 0 0 0 7 0 14 0 7 0 % M
% Asn: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % N
% Pro: 7 0 7 0 0 0 0 0 0 0 7 7 7 0 0 % P
% Gln: 0 0 0 0 14 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 7 0 7 20 0 0 7 60 0 0 14 0 14 % R
% Ser: 14 0 0 14 0 7 0 0 14 7 0 14 0 14 0 % S
% Thr: 7 7 0 0 0 0 0 0 0 7 0 0 0 0 0 % T
% Val: 0 0 0 7 54 0 0 7 0 0 7 7 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 54 0 0 0 0 7 67 0 0 20 0 14 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _