KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANAPC5
All Species:
28.79
Human Site:
S421
Identified Species:
63.33
UniProt:
Q9UJX4
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJX4
NP_057321.2
755
85077
S421
L
S
E
L
I
D
I
S
I
A
Q
K
T
A
I
Chimpanzee
Pan troglodytes
XP_001166003
803
90788
S469
L
S
E
L
I
D
I
S
I
A
Q
K
T
A
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534668
755
85070
S421
L
S
E
L
I
D
I
S
I
A
Q
K
T
A
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTZ4
740
83079
S406
L
S
E
L
I
D
I
S
I
A
Q
K
T
A
I
Rat
Rattus norvegicus
A1L1K3
727
81721
R406
A
I
W
R
L
Y
G
R
S
T
M
A
L
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521612
465
52155
S185
T
R
A
L
T
P
A
S
L
Q
K
E
L
N
N
Chicken
Gallus gallus
Q5ZKK3
756
85288
S421
L
S
E
L
I
D
I
S
I
A
Q
K
T
A
I
Frog
Xenopus laevis
NP_001090413
319
36081
V39
P
Y
K
I
S
V
L
V
L
L
S
E
M
S
K
Zebra Danio
Brachydanio rerio
NP_955916
761
85884
S427
L
S
E
L
I
E
I
S
L
A
Q
T
T
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393771
726
81963
T397
M
I
D
L
M
S
M
T
Y
A
E
K
S
A
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792445
716
81131
S406
H
R
I
M
S
S
L
S
D
Q
L
L
L
N
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94
N.A.
97.8
N.A.
92.8
91.5
N.A.
55.6
85.3
30.3
65.8
N.A.
N.A.
32.9
N.A.
29.8
Protein Similarity:
100
94
N.A.
99.4
N.A.
96.6
94.8
N.A.
58.1
92.7
37.2
81.3
N.A.
N.A.
53.3
N.A.
52.1
P-Site Identity:
100
100
N.A.
100
N.A.
100
0
N.A.
13.3
100
0
73.3
N.A.
N.A.
26.6
N.A.
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
6.6
N.A.
33.3
100
40
93.3
N.A.
N.A.
80
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
0
0
10
0
0
64
0
10
0
55
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
46
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
55
0
0
10
0
0
0
0
10
19
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
19
10
10
55
0
55
0
46
0
0
0
0
0
55
% I
% Lys:
0
0
10
0
0
0
0
0
0
0
10
55
0
0
10
% K
% Leu:
55
0
0
73
10
0
19
0
28
10
10
10
28
0
10
% L
% Met:
10
0
0
10
10
0
10
0
0
0
10
0
10
0
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
19
10
% N
% Pro:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
19
55
0
0
10
10
% Q
% Arg:
0
19
0
10
0
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
0
55
0
0
19
19
0
73
10
0
10
0
10
19
0
% S
% Thr:
10
0
0
0
10
0
0
10
0
10
0
10
55
0
0
% T
% Val:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
10
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _