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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANAPC2
All Species:
35.45
Human Site:
S377
Identified Species:
70.91
UniProt:
Q9UJX6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJX6
NP_037498.1
822
93828
S377
Q
R
Q
Q
L
L
V
S
L
K
A
A
L
E
T
Chimpanzee
Pan troglodytes
XP_520643
822
93623
S377
Q
R
Q
Q
L
L
V
S
L
K
A
A
L
E
T
Rhesus Macaque
Macaca mulatta
XP_001089959
822
93819
S377
Q
R
Q
Q
L
L
V
S
L
K
A
A
L
E
T
Dog
Lupus familis
XP_548357
818
93512
S373
Q
R
Q
Q
L
L
L
S
L
K
A
A
L
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZQ7
837
95302
S392
Q
R
Q
Q
L
L
V
S
L
K
V
A
L
E
T
Rat
Rattus norvegicus
NP_001094002
836
95354
S391
Q
R
Q
Q
L
L
V
S
L
K
V
A
L
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415533
810
92419
S365
L
R
Q
Q
L
L
S
S
L
K
S
A
L
E
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002662165
802
90907
S355
Q
R
Q
Q
L
L
A
S
L
K
S
A
F
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395411
604
69914
T203
A
L
R
Q
L
D
P
T
G
V
L
L
E
T
I
Nematode Worm
Caenorhab. elegans
P34514
731
84494
Y330
T
V
Q
Q
I
I
S
Y
I
T
S
N
K
K
N
Sea Urchin
Strong. purpuratus
XP_795679
445
51396
E44
I
V
L
E
L
V
C
E
P
I
R
K
Y
L
R
Poplar Tree
Populus trichocarpa
XP_002311316
870
97541
S398
Q
H
S
K
L
V
E
S
F
I
S
A
L
R
Y
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.9
99.3
95.2
N.A.
92.7
93.5
N.A.
N.A.
70.3
N.A.
54.8
N.A.
N.A.
36.9
25.2
28.8
Protein Similarity:
100
97
99.7
97.1
N.A.
94.9
95.6
N.A.
N.A.
84
N.A.
71.6
N.A.
N.A.
53.1
45.1
40.8
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
73.3
N.A.
80
N.A.
N.A.
13.3
13.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
80
N.A.
86.6
N.A.
N.A.
26.6
46.6
20
Percent
Protein Identity:
32
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
51.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
9
0
0
0
34
75
0
0
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
9
0
0
9
9
0
0
0
0
9
67
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% G
% His:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
9
9
0
0
9
17
0
0
0
0
17
% I
% Lys:
0
0
0
9
0
0
0
0
0
67
0
9
9
9
0
% K
% Leu:
9
9
9
0
92
67
9
0
67
0
9
9
67
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% N
% Pro:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% P
% Gln:
67
0
75
84
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
67
9
0
0
0
0
0
0
0
9
0
0
9
9
% R
% Ser:
0
0
9
0
0
0
17
75
0
0
34
0
0
0
0
% S
% Thr:
9
0
0
0
0
0
0
9
0
9
0
0
0
9
59
% T
% Val:
0
17
0
0
0
17
42
0
0
9
17
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
0
0
0
9
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _