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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANAPC2
All Species:
29.7
Human Site:
S493
Identified Species:
59.39
UniProt:
Q9UJX6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJX6
NP_037498.1
822
93828
S493
D
A
D
P
G
K
S
S
S
K
R
R
S
S
D
Chimpanzee
Pan troglodytes
XP_520643
822
93623
S493
D
A
D
P
G
K
S
S
S
K
A
R
S
S
D
Rhesus Macaque
Macaca mulatta
XP_001089959
822
93819
S493
D
A
D
P
G
K
S
S
S
K
R
R
S
S
D
Dog
Lupus familis
XP_548357
818
93512
S489
D
A
D
P
G
K
S
S
S
K
R
R
S
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZQ7
837
95302
S508
D
A
D
P
V
K
S
S
S
K
R
R
S
S
D
Rat
Rattus norvegicus
NP_001094002
836
95354
S507
D
A
D
P
A
K
S
S
S
K
R
R
S
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415533
810
92419
S481
D
A
D
P
G
K
S
S
S
K
R
R
S
S
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002662165
802
90907
G470
D
A
L
T
D
K
T
G
S
K
R
R
S
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395411
604
69914
Q316
L
A
D
R
L
L
S
Q
L
N
Y
H
T
E
R
Nematode Worm
Caenorhab. elegans
P34514
731
84494
D443
E
F
E
K
R
Y
L
D
L
L
K
L
R
F
Q
Sea Urchin
Strong. purpuratus
XP_795679
445
51396
Y157
R
I
L
S
S
F
S
Y
D
T
A
R
E
L
R
Poplar Tree
Populus trichocarpa
XP_002311316
870
97541
S528
E
A
D
P
L
K
G
S
R
N
Q
R
K
V
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.9
99.3
95.2
N.A.
92.7
93.5
N.A.
N.A.
70.3
N.A.
54.8
N.A.
N.A.
36.9
25.2
28.8
Protein Similarity:
100
97
99.7
97.1
N.A.
94.9
95.6
N.A.
N.A.
84
N.A.
71.6
N.A.
N.A.
53.1
45.1
40.8
P-Site Identity:
100
93.3
100
100
N.A.
93.3
93.3
N.A.
N.A.
100
N.A.
66.6
N.A.
N.A.
20
0
13.3
P-Site Similarity:
100
93.3
100
100
N.A.
93.3
93.3
N.A.
N.A.
100
N.A.
73.3
N.A.
N.A.
26.6
20
13.3
Percent
Protein Identity:
32
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
51.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
60
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
84
0
0
9
0
0
0
0
0
17
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
67
0
75
0
9
0
0
9
9
0
0
0
0
0
75
% D
% Glu:
17
0
9
0
0
0
0
0
0
0
0
0
9
9
0
% E
% Phe:
0
9
0
0
0
9
0
0
0
0
0
0
0
9
0
% F
% Gly:
0
0
0
0
42
0
9
9
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
9
0
75
0
0
0
67
9
0
9
0
0
% K
% Leu:
9
0
17
0
17
9
9
0
17
9
0
9
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% N
% Pro:
0
0
0
67
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
9
0
0
9
0
0
0
9
% Q
% Arg:
9
0
0
9
9
0
0
0
9
0
59
84
9
0
17
% R
% Ser:
0
0
0
9
9
0
75
67
67
0
0
0
67
67
0
% S
% Thr:
0
0
0
9
0
0
9
0
0
9
0
0
9
0
0
% T
% Val:
0
0
0
0
9
0
0
0
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
9
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _