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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANAPC2
All Species:
31.82
Human Site:
Y519
Identified Species:
63.64
UniProt:
Q9UJX6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJX6
NP_037498.1
822
93828
Y519
K
D
L
F
I
N
E
Y
R
S
L
L
A
D
R
Chimpanzee
Pan troglodytes
XP_520643
822
93623
X519
K
D
L
F
H
H
E
X
X
X
X
R
Q
I
N
Rhesus Macaque
Macaca mulatta
XP_001089959
822
93819
Y519
K
D
L
F
I
N
E
Y
R
S
L
L
A
D
R
Dog
Lupus familis
XP_548357
818
93512
Y515
K
D
L
F
I
N
E
Y
R
S
L
L
A
D
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZQ7
837
95302
Y534
K
D
L
F
I
N
E
Y
R
S
L
L
A
D
R
Rat
Rattus norvegicus
NP_001094002
836
95354
Y533
K
D
L
F
I
N
E
Y
R
S
L
L
A
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415533
810
92419
Y507
K
D
L
F
I
N
E
Y
R
T
L
L
A
D
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002662165
802
90907
Y496
K
E
I
F
V
N
E
Y
K
T
V
L
A
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395411
604
69914
Y342
F
G
E
N
Q
L
H
Y
C
E
V
M
L
K
D
Nematode Worm
Caenorhab. elegans
P34514
731
84494
D469
R
D
V
I
H
S
L
D
I
D
K
K
F
E
D
Sea Urchin
Strong. purpuratus
XP_795679
445
51396
V183
T
Q
L
H
Q
C
E
V
M
L
K
D
V
A
D
Poplar Tree
Populus trichocarpa
XP_002311316
870
97541
Y554
K
D
Q
L
V
N
E
Y
R
V
M
L
A
E
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.9
99.3
95.2
N.A.
92.7
93.5
N.A.
N.A.
70.3
N.A.
54.8
N.A.
N.A.
36.9
25.2
28.8
Protein Similarity:
100
97
99.7
97.1
N.A.
94.9
95.6
N.A.
N.A.
84
N.A.
71.6
N.A.
N.A.
53.1
45.1
40.8
P-Site Identity:
100
33.3
100
100
N.A.
100
100
N.A.
N.A.
93.3
N.A.
60
N.A.
N.A.
6.6
6.6
13.3
P-Site Similarity:
100
40
100
100
N.A.
100
100
N.A.
N.A.
100
N.A.
100
N.A.
N.A.
20
33.3
13.3
Percent
Protein Identity:
32
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
51.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
80
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
67
9
0
% A
% Cys:
0
0
0
0
0
9
0
0
9
0
0
0
0
0
0
% C
% Asp:
0
75
0
0
0
0
0
9
0
9
0
9
0
59
25
% D
% Glu:
0
9
9
0
0
0
84
0
0
9
0
0
0
17
0
% E
% Phe:
9
0
0
67
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
9
17
9
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
9
50
0
0
0
9
0
0
0
0
9
0
% I
% Lys:
75
0
0
0
0
0
0
0
9
0
17
9
0
9
9
% K
% Leu:
0
0
67
9
0
9
9
0
0
9
50
67
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
9
9
0
0
0
% M
% Asn:
0
0
0
9
0
67
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
9
0
17
0
0
0
0
0
0
0
9
0
0
% Q
% Arg:
9
0
0
0
0
0
0
0
59
0
0
9
0
0
59
% R
% Ser:
0
0
0
0
0
9
0
0
0
42
0
0
0
0
0
% S
% Thr:
9
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% T
% Val:
0
0
9
0
17
0
0
9
0
9
17
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
75
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _