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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HSPB8 All Species: 14.85
Human Site: S175 Identified Species: 36.3
UniProt: Q9UJY1 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UJY1 NP_055180.1 196 21604 S175 A P Q V P P Y S T F G E S S F
Chimpanzee Pan troglodytes XP_001157935 244 27761 C175 I V T R V G G C G H L K K Y H
Rhesus Macaque Macaca mulatta Q6SJQ8 195 21340 S174 A P Q V P P Y S T F G E S S F
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9JK92 196 21515 S175 A P Q V P P Y S P F G E S S F
Rat Rattus norvegicus Q9EPX0 196 21574 S175 A P Q V P P Y S P F G E S S F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q00649 193 21653 I172 A P L P K P A I Q S S E I T I
Frog Xenopus laevis NP_001079782 203 22699 N182 A P L V P P Y N Q Q G D D S Y
Zebra Danio Brachydanio rerio NP_001094427 216 24386 Y183 A R Q T P P Y Y L Y S N E M P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P82147 187 21290 I167 Q T E R L V Q I T Q T G P S S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784059 206 23120 P186 A P R N P P K P K N Q N I P I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 66.3 96.9 N.A. N.A. 94.3 95.4 N.A. N.A. 36.2 63.5 55.5 N.A. 37.2 N.A. N.A. 30.1
Protein Similarity: 100 68.4 96.9 N.A. N.A. 96.9 97.4 N.A. N.A. 52 73.4 67.1 N.A. 54 N.A. N.A. 46.6
P-Site Identity: 100 0 100 N.A. N.A. 93.3 93.3 N.A. N.A. 26.6 53.3 33.3 N.A. 13.3 N.A. N.A. 26.6
P-Site Similarity: 100 6.6 100 N.A. N.A. 93.3 93.3 N.A. N.A. 33.3 73.3 40 N.A. 20 N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 80 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 10 10 0 0 % D
% Glu: 0 0 10 0 0 0 0 0 0 0 0 50 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 40 0 0 0 0 40 % F
% Gly: 0 0 0 0 0 10 10 0 10 0 50 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 10 % H
% Ile: 10 0 0 0 0 0 0 20 0 0 0 0 20 0 20 % I
% Lys: 0 0 0 0 10 0 10 0 10 0 0 10 10 0 0 % K
% Leu: 0 0 20 0 10 0 0 0 10 0 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 0 0 0 10 0 0 0 10 0 10 0 20 0 0 0 % N
% Pro: 0 70 0 10 70 80 0 10 20 0 0 0 10 10 10 % P
% Gln: 10 0 50 0 0 0 10 0 20 20 10 0 0 0 0 % Q
% Arg: 0 10 10 20 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 40 0 10 20 0 40 60 10 % S
% Thr: 0 10 10 10 0 0 0 0 30 0 10 0 0 10 0 % T
% Val: 0 10 0 50 10 10 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 60 10 0 10 0 0 0 10 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _