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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HSPB8 All Species: 18.48
Human Site: S181 Identified Species: 45.19
UniProt: Q9UJY1 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UJY1 NP_055180.1 196 21604 S181 Y S T F G E S S F N N E L P Q
Chimpanzee Pan troglodytes XP_001157935 244 27761 Y181 G C G H L K K Y H R G S L Y C
Rhesus Macaque Macaca mulatta Q6SJQ8 195 21340 S180 Y S T F G E S S F N N E L P Q
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9JK92 196 21515 S181 Y S P F G E S S F N N E L P Q
Rat Rattus norvegicus Q9EPX0 196 21574 S181 Y S P F G E S S F N N E L P Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q00649 193 21653 T178 A I Q S S E I T I P V T V E A
Frog Xenopus laevis NP_001079782 203 22699 S188 Y N Q Q G D D S Y T Y E L P L
Zebra Danio Brachydanio rerio NP_001094427 216 24386 M189 Y Y L Y S N E M P A E S M E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P82147 187 21290 S173 Q I T Q T G P S S K E D N A K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784059 206 23120 P192 K P K N Q N I P I K V E S K P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 66.3 96.9 N.A. N.A. 94.3 95.4 N.A. N.A. 36.2 63.5 55.5 N.A. 37.2 N.A. N.A. 30.1
Protein Similarity: 100 68.4 96.9 N.A. N.A. 96.9 97.4 N.A. N.A. 52 73.4 67.1 N.A. 54 N.A. N.A. 46.6
P-Site Identity: 100 6.6 100 N.A. N.A. 93.3 93.3 N.A. N.A. 6.6 40 6.6 N.A. 13.3 N.A. N.A. 6.6
P-Site Similarity: 100 13.3 100 N.A. N.A. 93.3 93.3 N.A. N.A. 20 60 26.6 N.A. 26.6 N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 0 0 10 0 0 0 10 10 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 0 0 0 0 10 10 0 0 0 0 10 0 0 0 % D
% Glu: 0 0 0 0 0 50 10 0 0 0 20 60 0 20 10 % E
% Phe: 0 0 0 40 0 0 0 0 40 0 0 0 0 0 0 % F
% Gly: 10 0 10 0 50 10 0 0 0 0 10 0 0 0 0 % G
% His: 0 0 0 10 0 0 0 0 10 0 0 0 0 0 0 % H
% Ile: 0 20 0 0 0 0 20 0 20 0 0 0 0 0 0 % I
% Lys: 10 0 10 0 0 10 10 0 0 20 0 0 0 10 10 % K
% Leu: 0 0 10 0 10 0 0 0 0 0 0 0 60 0 10 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 0 % M
% Asn: 0 10 0 10 0 20 0 0 0 40 40 0 10 0 0 % N
% Pro: 0 10 20 0 0 0 10 10 10 10 0 0 0 50 10 % P
% Gln: 10 0 20 20 10 0 0 0 0 0 0 0 0 0 40 % Q
% Arg: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % R
% Ser: 0 40 0 10 20 0 40 60 10 0 0 20 10 0 0 % S
% Thr: 0 0 30 0 10 0 0 10 0 10 0 10 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 20 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 60 10 0 10 0 0 0 10 10 0 10 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _