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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GDF2
All Species:
9.09
Human Site:
S277
Identified Species:
18.18
UniProt:
Q9UK05
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UK05
NP_057288.1
429
47320
S277
L
E
L
R
E
M
I
S
H
E
Q
E
S
V
L
Chimpanzee
Pan troglodytes
XP_507775
429
47314
S277
L
E
L
R
E
M
I
S
H
E
Q
E
S
V
L
Rhesus Macaque
Macaca mulatta
XP_001109523
429
47622
S277
L
E
L
R
E
M
I
S
H
E
Q
E
S
V
L
Dog
Lupus familis
XP_853886
416
45419
H265
E
L
R
E
M
I
S
H
E
Q
D
S
V
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV56
428
47642
G276
L
E
L
K
E
M
I
G
H
E
Q
E
T
M
L
Rat
Rattus norvegicus
Q4AEG6
421
47748
L270
D
K
E
Q
K
E
E
L
N
E
L
I
S
H
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507701
433
49108
E277
E
T
R
M
E
L
R
E
M
I
G
H
E
Q
D
Chicken
Gallus gallus
P34822
427
48608
R275
K
E
T
K
V
E
L
R
E
M
I
V
H
E
Q
Frog
Xenopus laevis
P30885
401
45970
I250
Y
Q
G
K
H
V
R
I
S
R
S
L
L
P
Q
Zebra Danio
Brachydanio rerio
P85857
404
46271
N253
T
R
S
K
K
R
E
N
L
F
N
E
M
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07713
588
65849
K437
A
H
E
R
W
Q
H
K
Q
P
L
L
F
T
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P48969
461
51863
E310
V
V
F
F
Q
R
N
E
E
V
I
A
T
N
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
96
73.4
N.A.
80.4
40
N.A.
67.4
60.6
27
28.8
N.A.
23.9
N.A.
N.A.
21.6
Protein Similarity:
100
99.7
98.1
81.3
N.A.
88.1
60.8
N.A.
80.1
74.5
42.1
43.3
N.A.
38.9
N.A.
N.A.
38.3
P-Site Identity:
100
100
100
0
N.A.
73.3
13.3
N.A.
6.6
6.6
0
6.6
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
100
100
20
N.A.
93.3
40
N.A.
13.3
20
20
26.6
N.A.
6.6
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% D
% Glu:
17
42
17
9
42
17
17
17
25
42
0
42
9
9
17
% E
% Phe:
0
0
9
9
0
0
0
0
0
9
0
0
9
0
0
% F
% Gly:
0
0
9
0
0
0
0
9
0
0
9
0
0
0
0
% G
% His:
0
9
0
0
9
0
9
9
34
0
0
9
9
9
0
% H
% Ile:
0
0
0
0
0
9
34
9
0
9
17
9
0
0
0
% I
% Lys:
9
9
0
34
17
0
0
9
0
0
0
0
0
9
0
% K
% Leu:
34
9
34
0
0
9
9
9
9
0
17
17
9
9
34
% L
% Met:
0
0
0
9
9
34
0
0
9
9
0
0
9
9
0
% M
% Asn:
0
0
0
0
0
0
9
9
9
0
9
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
0
% P
% Gln:
0
9
0
9
9
9
0
0
9
9
34
0
0
9
17
% Q
% Arg:
0
9
17
34
0
17
17
9
0
9
0
0
0
0
0
% R
% Ser:
0
0
9
0
0
0
9
25
9
0
9
9
34
0
9
% S
% Thr:
9
9
9
0
0
0
0
0
0
0
0
0
17
9
9
% T
% Val:
9
9
0
0
9
9
0
0
0
9
0
9
9
25
0
% V
% Trp:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _