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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GDF2 All Species: 10.61
Human Site: S288 Identified Species: 21.21
UniProt: Q9UK05 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UK05 NP_057288.1 429 47320 S288 E S V L K K L S K D G S T E A
Chimpanzee Pan troglodytes XP_507775 429 47314 S288 E S V L K K L S K D G S T E A
Rhesus Macaque Macaca mulatta XP_001109523 429 47622 S288 E S V L K K L S K E G S T E A
Dog Lupus familis XP_853886 416 45419 K276 S V L T K W S K N S P A G A G
Cat Felis silvestris
Mouse Mus musculus Q9WV56 428 47642 A287 E T M L V K T A K N A Y Q G A
Rat Rattus norvegicus Q4AEG6 421 47748 D281 I S H E Q D L D L G T D G F F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507701 433 49108 R288 H E Q D S M L R K L S R N G P
Chicken Gallus gallus P34822 427 48608 L286 V H E Q E S V L N K L G K N D
Frog Xenopus laevis P30885 401 45970 D261 L L P Q K D A D W S Q M R P L
Zebra Danio Brachydanio rerio P85857 404 46271 S264 E M K E K I K S R G D D D E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P07713 588 65849 G448 L F T Y T D D G R H K A R S I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P48969 461 51863 R321 A T N S H L R R N R R A A T R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 96 73.4 N.A. 80.4 40 N.A. 67.4 60.6 27 28.8 N.A. 23.9 N.A. N.A. 21.6
Protein Similarity: 100 99.7 98.1 81.3 N.A. 88.1 60.8 N.A. 80.1 74.5 42.1 43.3 N.A. 38.9 N.A. N.A. 38.3
P-Site Identity: 100 100 93.3 6.6 N.A. 33.3 13.3 N.A. 13.3 0 6.6 26.6 N.A. 0 N.A. N.A. 0
P-Site Similarity: 100 100 100 20 N.A. 60 20 N.A. 13.3 13.3 6.6 33.3 N.A. 13.3 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 0 9 9 0 0 9 25 9 9 34 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 9 0 25 9 17 0 17 9 17 9 0 9 % D
% Glu: 42 9 9 17 9 0 0 0 0 9 0 0 0 34 9 % E
% Phe: 0 9 0 0 0 0 0 0 0 0 0 0 0 9 9 % F
% Gly: 0 0 0 0 0 0 0 9 0 17 25 9 17 17 9 % G
% His: 9 9 9 0 9 0 0 0 0 9 0 0 0 0 0 % H
% Ile: 9 0 0 0 0 9 0 0 0 0 0 0 0 0 9 % I
% Lys: 0 0 9 0 50 34 9 9 42 9 9 0 9 0 0 % K
% Leu: 17 9 9 34 0 9 42 9 9 9 9 0 0 0 9 % L
% Met: 0 9 9 0 0 9 0 0 0 0 0 9 0 0 0 % M
% Asn: 0 0 9 0 0 0 0 0 25 9 0 0 9 9 0 % N
% Pro: 0 0 9 0 0 0 0 0 0 0 9 0 0 9 9 % P
% Gln: 0 0 9 17 9 0 0 0 0 0 9 0 9 0 0 % Q
% Arg: 0 0 0 0 0 0 9 17 17 9 9 9 17 0 9 % R
% Ser: 9 34 0 9 9 9 9 34 0 17 9 25 0 9 0 % S
% Thr: 0 17 9 9 9 0 9 0 0 0 9 0 25 9 0 % T
% Val: 9 9 25 0 9 0 9 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 9 0 0 9 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 0 0 0 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _