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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GDF2
All Species:
23.03
Human Site:
Y354
Identified Species:
46.06
UniProt:
Q9UK05
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UK05
NP_057288.1
429
47320
Y354
A
P
K
E
Y
E
A
Y
E
C
K
G
G
C
F
Chimpanzee
Pan troglodytes
XP_507775
429
47314
Y354
A
P
K
E
Y
E
A
Y
E
C
K
G
G
C
F
Rhesus Macaque
Macaca mulatta
XP_001109523
429
47622
Y354
A
P
K
E
Y
E
A
Y
E
C
K
G
G
C
F
Dog
Lupus familis
XP_853886
416
45419
E342
P
K
E
Y
D
A
Y
E
C
K
G
G
C
F
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV56
428
47642
Y353
A
P
K
E
Y
D
A
Y
E
C
K
G
G
C
F
Rat
Rattus norvegicus
Q4AEG6
421
47748
Y347
A
P
P
G
Y
E
A
Y
E
C
R
G
V
C
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507701
433
49108
E354
S
W
I
I
A
P
T
E
Y
D
A
Y
E
C
K
Chicken
Gallus gallus
P34822
427
48608
F352
A
P
K
D
Y
E
A
F
E
C
K
G
G
C
F
Frog
Xenopus laevis
P30885
401
45970
A327
V
A
P
P
G
Y
Q
A
F
Y
C
H
G
D
C
Zebra Danio
Brachydanio rerio
P85857
404
46271
Y330
A
P
L
D
Y
E
A
Y
H
C
E
G
V
C
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07713
588
65849
Y514
A
P
L
G
Y
D
A
Y
Y
C
H
G
K
C
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P48969
461
51863
F387
A
P
L
G
Y
V
A
F
Y
C
Q
G
E
C
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
96
73.4
N.A.
80.4
40
N.A.
67.4
60.6
27
28.8
N.A.
23.9
N.A.
N.A.
21.6
Protein Similarity:
100
99.7
98.1
81.3
N.A.
88.1
60.8
N.A.
80.1
74.5
42.1
43.3
N.A.
38.9
N.A.
N.A.
38.3
P-Site Identity:
100
100
100
13.3
N.A.
93.3
66.6
N.A.
6.6
86.6
6.6
60
N.A.
53.3
N.A.
N.A.
46.6
P-Site Similarity:
100
100
100
20
N.A.
100
73.3
N.A.
13.3
100
6.6
73.3
N.A.
60
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
75
9
0
0
9
9
75
9
0
0
9
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
9
75
9
0
9
84
9
% C
% Asp:
0
0
0
17
9
17
0
0
0
9
0
0
0
9
9
% D
% Glu:
0
0
9
34
0
50
0
17
50
0
9
0
17
0
0
% E
% Phe:
0
0
0
0
0
0
0
17
9
0
0
0
0
9
50
% F
% Gly:
0
0
0
25
9
0
0
0
0
0
9
84
50
0
0
% G
% His:
0
0
0
0
0
0
0
0
9
0
9
9
0
0
0
% H
% Ile:
0
0
9
9
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
42
0
0
0
0
0
0
9
42
0
9
0
9
% K
% Leu:
0
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
9
75
17
9
0
9
0
0
0
0
0
0
0
0
9
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% R
% Ser:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% T
% Val:
9
0
0
0
0
9
0
0
0
0
0
0
17
0
0
% V
% Trp:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
75
9
9
59
25
9
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _