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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPS6KA6 All Species: 36.06
Human Site: Y474 Identified Species: 79.33
UniProt: Q9UK32 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UK32 NP_055311.1 745 83872 Y474 E I E I L M R Y G Q H P N I I
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001104305 745 83841 Y474 E I E I L M R Y G Q H P N I I
Dog Lupus familis XP_549109 744 83817 Y473 E I E I L M R Y G Q H P N I I
Cat Felis silvestris
Mouse Mus musculus Q7TPS0 764 86553 Y494 E I E I L M R Y G Q H P N I I
Rat Rattus norvegicus Q63531 735 82865 Y466 E I E I L L R Y G Q H P N I I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518212 773 86651 Y502 E I E I L M R Y G Q H P N I I
Chicken Gallus gallus P18652 752 84421 Y483 E I E I L L R Y G Q H P N I I
Frog Xenopus laevis P10665 733 82620 Y464 E I E I L R R Y G Q H P N I I
Zebra Danio Brachydanio rerio Q6PFQ0 740 83378 Y468 E I E I L M R Y G Q H P N I I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3I5 1207 137026 A671 V D A L I S C A L D T T N H K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q21734 784 88102 H502 E V D I L L R H S H H Q F V V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.3 94.7 N.A. 85.3 72.8 N.A. 80.5 74.4 71.6 83.8 N.A. 24.4 N.A. 55 N.A.
Protein Similarity: 100 N.A. 99.4 97.8 N.A. 90.9 83.7 N.A. 87 84 81.7 90.4 N.A. 35.9 N.A. 69.3 N.A.
P-Site Identity: 100 N.A. 100 100 N.A. 100 93.3 N.A. 100 93.3 93.3 100 N.A. 6.6 N.A. 33.3 N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 100 100 93.3 100 N.A. 20 N.A. 73.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 0 10 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 10 0 0 0 0 0 0 10 0 0 0 0 0 % D
% Glu: 91 0 82 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 82 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 10 0 10 91 0 0 10 0 % H
% Ile: 0 82 0 91 10 0 0 0 0 0 0 0 0 82 82 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % K
% Leu: 0 0 0 10 91 28 0 0 10 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 55 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 91 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 82 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 82 0 10 0 0 0 % Q
% Arg: 0 0 0 0 0 10 91 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 10 0 0 10 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % T
% Val: 10 10 0 0 0 0 0 0 0 0 0 0 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 82 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _