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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA6
All Species:
36.06
Human Site:
Y474
Identified Species:
79.33
UniProt:
Q9UK32
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UK32
NP_055311.1
745
83872
Y474
E
I
E
I
L
M
R
Y
G
Q
H
P
N
I
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001104305
745
83841
Y474
E
I
E
I
L
M
R
Y
G
Q
H
P
N
I
I
Dog
Lupus familis
XP_549109
744
83817
Y473
E
I
E
I
L
M
R
Y
G
Q
H
P
N
I
I
Cat
Felis silvestris
Mouse
Mus musculus
Q7TPS0
764
86553
Y494
E
I
E
I
L
M
R
Y
G
Q
H
P
N
I
I
Rat
Rattus norvegicus
Q63531
735
82865
Y466
E
I
E
I
L
L
R
Y
G
Q
H
P
N
I
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518212
773
86651
Y502
E
I
E
I
L
M
R
Y
G
Q
H
P
N
I
I
Chicken
Gallus gallus
P18652
752
84421
Y483
E
I
E
I
L
L
R
Y
G
Q
H
P
N
I
I
Frog
Xenopus laevis
P10665
733
82620
Y464
E
I
E
I
L
R
R
Y
G
Q
H
P
N
I
I
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
Y468
E
I
E
I
L
M
R
Y
G
Q
H
P
N
I
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
A671
V
D
A
L
I
S
C
A
L
D
T
T
N
H
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21734
784
88102
H502
E
V
D
I
L
L
R
H
S
H
H
Q
F
V
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.3
94.7
N.A.
85.3
72.8
N.A.
80.5
74.4
71.6
83.8
N.A.
24.4
N.A.
55
N.A.
Protein Similarity:
100
N.A.
99.4
97.8
N.A.
90.9
83.7
N.A.
87
84
81.7
90.4
N.A.
35.9
N.A.
69.3
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
93.3
N.A.
100
93.3
93.3
100
N.A.
6.6
N.A.
33.3
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
100
93.3
100
N.A.
20
N.A.
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
0
0
0
0
0
0
10
0
0
0
0
0
% D
% Glu:
91
0
82
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
82
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
10
91
0
0
10
0
% H
% Ile:
0
82
0
91
10
0
0
0
0
0
0
0
0
82
82
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% K
% Leu:
0
0
0
10
91
28
0
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
55
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
91
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
82
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
82
0
10
0
0
0
% Q
% Arg:
0
0
0
0
0
10
91
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% T
% Val:
10
10
0
0
0
0
0
0
0
0
0
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
82
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _