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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZNF580 All Species: 15.15
Human Site: S136 Identified Species: 41.67
UniProt: Q9UK33 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UK33 NP_001156895.1 172 18756 S136 F K R S S H L S R H R A T H R
Chimpanzee Pan troglodytes XP_001137881 194 21847 A128 F K R A S H L A R H H S I H L
Rhesus Macaque Macaca mulatta XP_001088380 265 28719 R159 F K R S S H L R R H C N I H A
Dog Lupus familis XP_853994 172 18752 S136 F K R S S H L S R H R A T H R
Cat Felis silvestris
Mouse Mus musculus Q9DB38 172 18818 S136 F K R S S H L S R H R A T H R
Rat Rattus norvegicus B1WBS3 420 46610 S376 F Q Y S H N L S R H A V V H T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P30373 509 56690 T431 F S Q G S H L T K H R R S H G
Frog Xenopus laevis P18722 280 32228 N218 F T Q K T N L N T H Q L T H T
Zebra Danio Brachydanio rerio XP_001919451 211 23823 N178 F S C S S H L N H H M M I H T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 45.3 27.5 98.2 N.A. 97 21.4 N.A. N.A. 20.2 20.7 21.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 53 36.9 98.2 N.A. 97 26.1 N.A. N.A. 23.7 31.7 33.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 60 66.6 100 N.A. 100 46.6 N.A. N.A. 46.6 33.3 46.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 80 66.6 100 N.A. 100 60 N.A. N.A. 73.3 66.6 53.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 12 0 0 0 12 0 0 12 34 0 0 12 % A
% Cys: 0 0 12 0 0 0 0 0 0 0 12 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 12 % G
% His: 0 0 0 0 12 78 0 0 12 100 12 0 0 100 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 34 0 0 % I
% Lys: 0 56 0 12 0 0 0 0 12 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 100 0 0 0 0 12 0 0 12 % L
% Met: 0 0 0 0 0 0 0 0 0 0 12 12 0 0 0 % M
% Asn: 0 0 0 0 0 23 0 23 0 0 0 12 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 12 23 0 0 0 0 0 0 0 12 0 0 0 0 % Q
% Arg: 0 0 56 0 0 0 0 12 67 0 45 12 0 0 34 % R
% Ser: 0 23 0 67 78 0 0 45 0 0 0 12 12 0 0 % S
% Thr: 0 12 0 0 12 0 0 12 12 0 0 0 45 0 34 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 12 12 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _