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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VPS28 All Species: 34.55
Human Site: S188 Identified Species: 54.29
UniProt: Q9UK41 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UK41 NP_057292.1 221 25425 S188 S Q W L Q T L S G M S A S D E
Chimpanzee Pan troglodytes XP_520017 227 25966 P188 S Q W W V S L P A R Q S P R S
Rhesus Macaque Macaca mulatta XP_001091900 221 25421 S188 S Q W L Q T L S G M S A S D E
Dog Lupus familis XP_849245 211 24427 S178 S Q W L Q T L S G M S A S D E
Cat Felis silvestris
Mouse Mus musculus Q9D1C8 221 25434 S188 S Q W L Q T L S G M S A S D E
Rat Rattus norvegicus B5DEN9 228 26091 S195 S Q W L Q T L S G M S A S D E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515562 139 15654 R108 R V S A R S A R E P Y D N M A
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_956884 223 25426 S189 S L W L T T L S S M S A S D E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V359 210 24493 N176 E K W L G S L N E M Q A S D E
Honey Bee Apis mellifera XP_392314 213 24558 N178 A E W L Q T L N N M S A S D E
Nematode Worm Caenorhab. elegans Q9NA26 210 24203 S174 K K W H D R L S S M A A S D E
Sea Urchin Strong. purpuratus XP_786883 224 25708 S188 N K W L T T M S S M R A A D E
Poplar Tree Populus trichocarpa XP_002305661 209 23287 S173 K E W I L R L S K M G A A D E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S9T7 210 23671 S174 K E W L S R L S K M G A A D E
Baker's Yeast Sacchar. cerevisiae Q02767 242 27684 N210 I D W I V R I N K L S I G D T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.6 99.5 93.6 N.A. 98.6 95.1 N.A. 47.5 N.A. N.A. 86.5 N.A. 59.7 67.8 42.9 59.3
Protein Similarity: 100 85.4 100 95.4 N.A. 100 96.9 N.A. 54.7 N.A. N.A. 93.7 N.A. 77.8 85.5 61.9 80.8
P-Site Identity: 100 26.6 100 100 N.A. 100 100 N.A. 0 N.A. N.A. 80 N.A. 53.3 73.3 53.3 53.3
P-Site Similarity: 100 40 100 100 N.A. 100 100 N.A. 20 N.A. N.A. 80 N.A. 73.3 93.3 66.6 80
Percent
Protein Identity: 36.6 N.A. N.A. 38.9 28.5 N.A.
Protein Similarity: 59.7 N.A. N.A. 59.7 52.8 N.A.
P-Site Identity: 46.6 N.A. N.A. 53.3 20 N.A.
P-Site Similarity: 66.6 N.A. N.A. 66.6 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 7 0 0 7 0 7 0 7 80 20 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 7 0 0 0 0 0 0 7 0 87 0 % D
% Glu: 7 20 0 0 0 0 0 0 14 0 0 0 0 0 80 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 7 0 0 0 34 0 14 0 7 0 0 % G
% His: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 0 0 14 0 0 7 0 0 0 0 7 0 0 0 % I
% Lys: 20 20 0 0 0 0 0 0 20 0 0 0 0 0 0 % K
% Leu: 0 7 0 67 7 0 80 0 0 7 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 7 0 0 80 0 0 0 7 0 % M
% Asn: 7 0 0 0 0 0 0 20 7 0 0 0 7 0 0 % N
% Pro: 0 0 0 0 0 0 0 7 0 7 0 0 7 0 0 % P
% Gln: 0 40 0 0 40 0 0 0 0 0 14 0 0 0 0 % Q
% Arg: 7 0 0 0 7 27 0 7 0 7 7 0 0 7 0 % R
% Ser: 47 0 7 0 7 20 0 67 20 0 54 7 60 0 7 % S
% Thr: 0 0 0 0 14 54 0 0 0 0 0 0 0 0 7 % T
% Val: 0 7 0 0 14 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 94 7 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _