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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS28
All Species:
26.06
Human Site:
S199
Identified Species:
40.95
UniProt:
Q9UK41
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UK41
NP_057292.1
221
25425
S199
A
S
D
E
L
D
D
S
Q
V
R
Q
M
L
F
Chimpanzee
Pan troglodytes
XP_520017
227
25966
A199
S
P
R
S
A
P
E
A
L
P
A
R
R
S
P
Rhesus Macaque
Macaca mulatta
XP_001091900
221
25421
S199
A
S
D
E
L
D
D
S
Q
V
R
Q
M
L
F
Dog
Lupus familis
XP_849245
211
24427
S189
A
S
D
E
L
D
D
S
Q
V
R
Q
M
L
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9D1C8
221
25434
S199
A
S
D
E
L
D
D
S
Q
V
R
Q
M
L
F
Rat
Rattus norvegicus
B5DEN9
228
26091
S206
A
S
D
E
L
D
D
S
Q
V
R
Q
M
L
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515562
139
15654
A45
D
N
M
A
E
L
F
A
V
V
K
T
L
Q
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956884
223
25426
S200
A
S
D
E
L
D
D
S
Q
V
R
Q
M
L
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V359
210
24493
G187
A
S
D
E
L
S
E
G
Q
V
R
Q
F
L
F
Honey Bee
Apis mellifera
XP_392314
213
24558
N189
A
S
D
E
L
S
D
N
Q
V
R
Q
L
I
F
Nematode Worm
Caenorhab. elegans
Q9NA26
210
24203
E185
A
S
D
E
I
S
D
E
D
A
R
Q
M
I
F
Sea Urchin
Strong. purpuratus
XP_786883
224
25708
E199
A
A
D
E
L
S
E
E
Q
I
R
Q
L
L
Y
Poplar Tree
Populus trichocarpa
XP_002305661
209
23287
Q184
A
A
D
E
L
T
E
Q
Q
A
R
Q
L
H
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S9T7
210
23671
Q185
A
A
D
E
L
T
E
Q
Q
S
R
Q
L
H
F
Baker's Yeast
Sacchar. cerevisiae
Q02767
242
27684
T221
I
G
D
T
L
T
E
T
Q
I
R
E
L
L
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.6
99.5
93.6
N.A.
98.6
95.1
N.A.
47.5
N.A.
N.A.
86.5
N.A.
59.7
67.8
42.9
59.3
Protein Similarity:
100
85.4
100
95.4
N.A.
100
96.9
N.A.
54.7
N.A.
N.A.
93.7
N.A.
77.8
85.5
61.9
80.8
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
6.6
N.A.
N.A.
100
N.A.
73.3
73.3
60
53.3
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
33.3
N.A.
N.A.
100
N.A.
80
93.3
73.3
86.6
Percent
Protein Identity:
36.6
N.A.
N.A.
38.9
28.5
N.A.
Protein Similarity:
59.7
N.A.
N.A.
59.7
52.8
N.A.
P-Site Identity:
53.3
N.A.
N.A.
53.3
40
N.A.
P-Site Similarity:
73.3
N.A.
N.A.
73.3
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
80
20
0
7
7
0
0
14
0
14
7
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
87
0
0
40
54
0
7
0
0
0
0
0
0
% D
% Glu:
0
0
0
80
7
0
40
14
0
0
0
7
0
0
0
% E
% Phe:
0
0
0
0
0
0
7
0
0
0
0
0
7
0
80
% F
% Gly:
0
7
0
0
0
0
0
7
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
14
0
% H
% Ile:
7
0
0
0
7
0
0
0
0
14
0
0
0
14
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% K
% Leu:
0
0
0
0
80
7
0
0
7
0
0
0
40
60
0
% L
% Met:
0
0
7
0
0
0
0
0
0
0
0
0
47
0
0
% M
% Asn:
0
7
0
0
0
0
0
7
0
0
0
0
0
0
0
% N
% Pro:
0
7
0
0
0
7
0
0
0
7
0
0
0
0
7
% P
% Gln:
0
0
0
0
0
0
0
14
80
0
0
80
0
7
0
% Q
% Arg:
0
0
7
0
0
0
0
0
0
0
87
7
7
0
0
% R
% Ser:
7
60
0
7
0
27
0
40
0
7
0
0
0
7
0
% S
% Thr:
0
0
0
7
0
20
0
7
0
0
0
7
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
7
60
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _