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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VPS28 All Species: 22.42
Human Site: S91 Identified Species: 35.24
UniProt: Q9UK41 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UK41 NP_057292.1 221 25425 S91 V Q G S E I S S I D E F C R K
Chimpanzee Pan troglodytes XP_520017 227 25966 S91 V Q G S E I S S I D E F C R K
Rhesus Macaque Macaca mulatta XP_001091900 221 25421 T91 V Q G S E I S T I D E F C R K
Dog Lupus familis XP_849245 211 24427 D92 F C R K F R L D C P L A M D R
Cat Felis silvestris
Mouse Mus musculus Q9D1C8 221 25434 S91 V Q G S E I S S I D E F C R K
Rat Rattus norvegicus B5DEN9 228 26091 S98 V Q G S E I S S I D E F C R K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515562 139 15654 R34 L Y K N A R E R E K Y D N M A
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_956884 223 25426 S92 V Q G S D V G S I D D F C R K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V359 210 24493 R97 D C P A A L E R I R E D R P I
Honey Bee Apis mellifera XP_392314 213 24558 D92 F A R A F R L D C P A A L E R
Nematode Worm Caenorhab. elegans Q9NA26 210 24203 A92 Y R L H C P A A I E R I R E G
Sea Urchin Strong. purpuratus XP_786883 224 25708 V92 V K G E F T S V E D F M K K Y
Poplar Tree Populus trichocarpa XP_002305661 209 23287 A95 L V T S G V P A T V E H R A A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S9T7 210 23671 A96 L V T S G L P A T V E H R A T
Baker's Yeast Sacchar. cerevisiae Q02767 242 27684 K92 Q N K E E I N K H F Q S I E A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.6 99.5 93.6 N.A. 98.6 95.1 N.A. 47.5 N.A. N.A. 86.5 N.A. 59.7 67.8 42.9 59.3
Protein Similarity: 100 85.4 100 95.4 N.A. 100 96.9 N.A. 54.7 N.A. N.A. 93.7 N.A. 77.8 85.5 61.9 80.8
P-Site Identity: 100 100 93.3 0 N.A. 100 100 N.A. 0 N.A. N.A. 73.3 N.A. 13.3 0 6.6 26.6
P-Site Similarity: 100 100 100 6.6 N.A. 100 100 N.A. 13.3 N.A. N.A. 93.3 N.A. 26.6 13.3 33.3 40
Percent
Protein Identity: 36.6 N.A. N.A. 38.9 28.5 N.A.
Protein Similarity: 59.7 N.A. N.A. 59.7 52.8 N.A.
P-Site Identity: 13.3 N.A. N.A. 13.3 13.3 N.A.
P-Site Similarity: 33.3 N.A. N.A. 33.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 14 14 0 7 20 0 0 7 14 0 14 20 % A
% Cys: 0 14 0 0 7 0 0 0 14 0 0 0 40 0 0 % C
% Asp: 7 0 0 0 7 0 0 14 0 47 7 14 0 7 0 % D
% Glu: 0 0 0 14 40 0 14 0 14 7 54 0 0 20 0 % E
% Phe: 14 0 0 0 20 0 0 0 0 7 7 40 0 0 0 % F
% Gly: 0 0 47 0 14 0 7 0 0 0 0 0 0 0 7 % G
% His: 0 0 0 7 0 0 0 0 7 0 0 14 0 0 0 % H
% Ile: 0 0 0 0 0 40 0 0 54 0 0 7 7 0 7 % I
% Lys: 0 7 14 7 0 0 0 7 0 7 0 0 7 7 40 % K
% Leu: 20 0 7 0 0 14 14 0 0 0 7 0 7 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 7 7 7 0 % M
% Asn: 0 7 0 7 0 0 7 0 0 0 0 0 7 0 0 % N
% Pro: 0 0 7 0 0 7 14 0 0 14 0 0 0 7 0 % P
% Gln: 7 40 0 0 0 0 0 0 0 0 7 0 0 0 0 % Q
% Arg: 0 7 14 0 0 20 0 14 0 7 7 0 27 40 14 % R
% Ser: 0 0 0 54 0 0 40 34 0 0 0 7 0 0 0 % S
% Thr: 0 0 14 0 0 7 0 7 14 0 0 0 0 0 7 % T
% Val: 47 14 0 0 0 14 0 7 0 14 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 7 0 0 0 0 0 0 0 0 7 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _