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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS28
All Species:
43.33
Human Site:
T117
Identified Species:
68.1
UniProt:
Q9UK41
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UK41
NP_057292.1
221
25425
T117
I
K
E
D
R
P
I
T
I
K
D
D
K
G
N
Chimpanzee
Pan troglodytes
XP_520017
227
25966
T117
I
K
E
D
R
P
I
T
I
K
D
D
K
G
N
Rhesus Macaque
Macaca mulatta
XP_001091900
221
25421
T117
I
K
E
D
R
P
I
T
I
K
D
D
K
G
N
Dog
Lupus familis
XP_849245
211
24427
T107
I
K
E
D
R
P
I
T
I
K
D
D
K
G
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9D1C8
221
25434
T117
I
K
E
D
R
P
I
T
I
K
D
D
K
G
N
Rat
Rattus norvegicus
B5DEN9
228
26091
T124
I
K
E
D
R
P
I
T
I
K
D
D
K
G
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515562
139
15654
T49
E
L
F
A
V
V
K
T
L
Q
A
L
E
K
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956884
223
25426
T118
I
K
E
D
R
P
I
T
I
K
D
D
K
G
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V359
210
24493
T113
I
R
D
D
K
G
N
T
S
K
C
I
A
E
I
Honey Bee
Apis mellifera
XP_392314
213
24558
T107
I
K
E
D
R
P
I
T
I
K
D
D
K
G
N
Nematode Worm
Caenorhab. elegans
Q9NA26
210
24203
V111
V
K
D
D
Q
G
N
V
L
K
H
I
A
S
I
Sea Urchin
Strong. purpuratus
XP_786883
224
25708
T117
I
K
E
D
R
P
I
T
I
K
K
D
D
G
N
Poplar Tree
Populus trichocarpa
XP_002305661
209
23287
S112
V
S
S
T
T
S
A
S
I
V
A
E
C
V
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S9T7
210
23671
S113
A
S
T
S
N
S
A
S
I
V
A
E
C
V
Q
Baker's Yeast
Sacchar. cerevisiae
Q02767
242
27684
S142
S
G
D
N
K
Q
S
S
S
S
D
K
K
F
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.6
99.5
93.6
N.A.
98.6
95.1
N.A.
47.5
N.A.
N.A.
86.5
N.A.
59.7
67.8
42.9
59.3
Protein Similarity:
100
85.4
100
95.4
N.A.
100
96.9
N.A.
54.7
N.A.
N.A.
93.7
N.A.
77.8
85.5
61.9
80.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
N.A.
N.A.
100
N.A.
26.6
100
20
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
26.6
N.A.
N.A.
100
N.A.
46.6
100
46.6
86.6
Percent
Protein Identity:
36.6
N.A.
N.A.
38.9
28.5
N.A.
Protein Similarity:
59.7
N.A.
N.A.
59.7
52.8
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
20
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
0
0
14
0
0
0
20
0
14
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
14
0
0
% C
% Asp:
0
0
20
74
0
0
0
0
0
0
60
60
7
0
0
% D
% Glu:
7
0
60
0
0
0
0
0
0
0
0
14
7
7
0
% E
% Phe:
0
0
7
0
0
0
0
0
0
0
0
0
0
7
0
% F
% Gly:
0
7
0
0
0
14
0
0
0
0
0
0
0
60
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
67
0
0
0
0
0
60
0
74
0
0
14
0
0
14
% I
% Lys:
0
67
0
0
14
0
7
0
0
74
7
7
60
7
0
% K
% Leu:
0
7
0
0
0
0
0
0
14
0
0
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
7
0
14
0
0
0
0
0
0
0
67
% N
% Pro:
0
0
0
0
0
60
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
7
7
0
0
0
7
0
0
0
0
14
% Q
% Arg:
0
7
0
0
60
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
7
14
7
7
0
14
7
20
14
7
0
0
0
7
0
% S
% Thr:
0
0
7
7
7
0
0
74
0
0
0
0
0
0
0
% T
% Val:
14
0
0
0
7
7
0
7
0
14
0
0
0
14
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _