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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VPS28 All Species: 22.12
Human Site: T179 Identified Species: 34.76
UniProt: Q9UK41 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.64
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UK41 NP_057292.1 221 25425 T179 P D F E G R Q T V S Q W L Q T
Chimpanzee Pan troglodytes XP_520017 227 25966 T179 P D F E G R Q T V S Q W W V S
Rhesus Macaque Macaca mulatta XP_001091900 221 25421 T179 P D F E G R Q T V S Q W L Q T
Dog Lupus familis XP_849245 211 24427 T169 P D F E G R Q T V S Q W L Q T
Cat Felis silvestris
Mouse Mus musculus Q9D1C8 221 25434 T179 P D F E G R Q T V S Q W L Q T
Rat Rattus norvegicus B5DEN9 228 26091 T186 P D F E G R Q T V S Q W L Q T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515562 139 15654 K99 S I D E F C R K F R V S A R S
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_956884 223 25426 K180 P D S E A K D K V S L W L T T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V359 210 24493 K167 E D F D A K L K V E K W L G S
Honey Bee Apis mellifera XP_392314 213 24558 K169 S D F D G K E K V A E W L Q T
Nematode Worm Caenorhab. elegans Q9NA26 210 24203 K165 I D A I V T T K V K K W H D R
Sea Urchin Strong. purpuratus XP_786883 224 25708 R179 A G Y D G K E R I N K W L T T
Poplar Tree Populus trichocarpa XP_002305661 209 23287 K164 P D F E G K T K M K E W I L R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S9T7 210 23671 K165 P D F E G K T K M K E W L S R
Baker's Yeast Sacchar. cerevisiae Q02767 242 27684 K201 D D F E N R S K L I D W I V R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.6 99.5 93.6 N.A. 98.6 95.1 N.A. 47.5 N.A. N.A. 86.5 N.A. 59.7 67.8 42.9 59.3
Protein Similarity: 100 85.4 100 95.4 N.A. 100 96.9 N.A. 54.7 N.A. N.A. 93.7 N.A. 77.8 85.5 61.9 80.8
P-Site Identity: 100 80 100 100 N.A. 100 100 N.A. 6.6 N.A. N.A. 53.3 N.A. 33.3 53.3 20 26.6
P-Site Similarity: 100 86.6 100 100 N.A. 100 100 N.A. 26.6 N.A. N.A. 60 N.A. 60 86.6 26.6 73.3
Percent
Protein Identity: 36.6 N.A. N.A. 38.9 28.5 N.A.
Protein Similarity: 59.7 N.A. N.A. 59.7 52.8 N.A.
P-Site Identity: 40 N.A. N.A. 46.6 33.3 N.A.
P-Site Similarity: 66.6 N.A. N.A. 66.6 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 0 14 0 0 0 0 7 0 0 7 0 0 % A
% Cys: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 87 7 20 0 0 7 0 0 0 7 0 0 7 0 % D
% Glu: 7 0 0 74 0 0 14 0 0 7 20 0 0 0 0 % E
% Phe: 0 0 74 0 7 0 0 0 7 0 0 0 0 0 0 % F
% Gly: 0 7 0 0 67 0 0 0 0 0 0 0 0 7 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % H
% Ile: 7 7 0 7 0 0 0 0 7 7 0 0 14 0 0 % I
% Lys: 0 0 0 0 0 40 0 54 0 20 20 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 7 0 7 0 7 0 67 7 0 % L
% Met: 0 0 0 0 0 0 0 0 14 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 7 0 0 0 0 7 0 0 0 0 0 % N
% Pro: 60 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 40 0 0 0 40 0 0 40 0 % Q
% Arg: 0 0 0 0 0 47 7 7 0 7 0 0 0 7 27 % R
% Ser: 14 0 7 0 0 0 7 0 0 47 0 7 0 7 20 % S
% Thr: 0 0 0 0 0 7 20 40 0 0 0 0 0 14 54 % T
% Val: 0 0 0 0 7 0 0 0 67 0 7 0 0 14 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 94 7 0 0 % W
% Tyr: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _