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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VPS28 All Species: 29.39
Human Site: Y27 Identified Species: 46.19
UniProt: Q9UK41 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UK41 NP_057292.1 221 25425 Y27 L Y E E V K L Y K N A R E R E
Chimpanzee Pan troglodytes XP_520017 227 25966 Y27 L Y E E V K L Y K N A R E R E
Rhesus Macaque Macaca mulatta XP_001091900 221 25421 Y27 L Y E E V K L Y K N A R E R E
Dog Lupus familis XP_849245 211 24427 N28 R E R E K Y D N M A E L F A V
Cat Felis silvestris
Mouse Mus musculus Q9D1C8 221 25434 Y27 L Y E E V K L Y K N A R E R E
Rat Rattus norvegicus B5DEN9 228 26091 Y34 L Y E E V K L Y K N A R E R E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515562 139 15654
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_956884 223 25426 Y28 L Y E E V K L Y K N A R E R E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V359 210 24493 I33 N M A D L Y A I I N T I Q Q L
Honey Bee Apis mellifera XP_392314 213 24558 N28 R E R E K H D N Q A D L Y A V
Nematode Worm Caenorhab. elegans Q9NA26 210 24203 S28 R E Q M E N L S E L F A V L N
Sea Urchin Strong. purpuratus XP_786883 224 25708 Y28 L Y E E V K L Y R N V R E R E
Poplar Tree Populus trichocarpa XP_002305661 209 23287 L31 I I K A T E K L E K A Y V R D
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S9T7 210 23671 L32 I I K A T E K L E K A Y I R D
Baker's Yeast Sacchar. cerevisiae Q02767 242 27684 S28 E V P L F D N S I T S K D K E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.6 99.5 93.6 N.A. 98.6 95.1 N.A. 47.5 N.A. N.A. 86.5 N.A. 59.7 67.8 42.9 59.3
Protein Similarity: 100 85.4 100 95.4 N.A. 100 96.9 N.A. 54.7 N.A. N.A. 93.7 N.A. 77.8 85.5 61.9 80.8
P-Site Identity: 100 100 100 6.6 N.A. 100 100 N.A. 0 N.A. N.A. 100 N.A. 6.6 6.6 6.6 86.6
P-Site Similarity: 100 100 100 6.6 N.A. 100 100 N.A. 0 N.A. N.A. 100 N.A. 33.3 13.3 20 93.3
Percent
Protein Identity: 36.6 N.A. N.A. 38.9 28.5 N.A.
Protein Similarity: 59.7 N.A. N.A. 59.7 52.8 N.A.
P-Site Identity: 13.3 N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: 46.6 N.A. N.A. 46.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 14 0 0 7 0 0 14 54 7 0 14 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 7 0 7 14 0 0 0 7 0 7 0 14 % D
% Glu: 7 20 47 60 7 14 0 0 20 0 7 0 47 0 54 % E
% Phe: 0 0 0 0 7 0 0 0 0 0 7 0 7 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % H
% Ile: 14 14 0 0 0 0 0 7 14 0 0 7 7 0 0 % I
% Lys: 0 0 14 0 14 47 14 0 40 14 0 7 0 7 0 % K
% Leu: 47 0 0 7 7 0 54 14 0 7 0 14 0 7 7 % L
% Met: 0 7 0 7 0 0 0 0 7 0 0 0 0 0 0 % M
% Asn: 7 0 0 0 0 7 7 14 0 54 0 0 0 0 7 % N
% Pro: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 7 0 0 0 0 0 7 0 0 0 7 7 0 % Q
% Arg: 20 0 14 0 0 0 0 0 7 0 0 47 0 60 0 % R
% Ser: 0 0 0 0 0 0 0 14 0 0 7 0 0 0 0 % S
% Thr: 0 0 0 0 14 0 0 0 0 7 7 0 0 0 0 % T
% Val: 0 7 0 0 47 0 0 0 0 0 7 0 14 0 14 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 47 0 0 0 14 0 47 0 0 0 14 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _