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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VPS28 All Species: 32.42
Human Site: Y66 Identified Species: 50.95
UniProt: Q9UK41 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UK41 NP_057292.1 221 25425 Y66 D C V S P S E Y T A A C S R L
Chimpanzee Pan troglodytes XP_520017 227 25966 Y66 D C V S P S E Y T A A C S R L
Rhesus Macaque Macaca mulatta XP_001091900 221 25421 Y66 D C V S P S E Y T A A C S R L
Dog Lupus familis XP_849245 211 24427 Y67 C S R L L V Q Y K A A F R Q V
Cat Felis silvestris
Mouse Mus musculus Q9D1C8 221 25434 Y66 D C V T P N E Y T A A C S R L
Rat Rattus norvegicus B5DEN9 228 26091 Y73 D C V T P N E Y T A A C S R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515562 139 15654 S9 F H G I P A P S A G P P A P G
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_956884 223 25426 Y67 D C V T P N E Y T G A C S R L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V359 210 24493 V72 Y K V A F K Q V Q C D E F P S
Honey Bee Apis mellifera XP_392314 213 24558 Y67 C S K L L V Q Y R A A F K Q V
Nematode Worm Caenorhab. elegans Q9NA26 210 24203 V67 K L I D Q Y K V T M R L V H G
Sea Urchin Strong. purpuratus XP_786883 224 25708 Y67 D A V P A K E Y T G S C S K L
Poplar Tree Populus trichocarpa XP_002305661 209 23287 I70 L K D T V P S I E R F A D T Y
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S9T7 210 23671 I71 L K D T V P N I E R F A D T Y
Baker's Yeast Sacchar. cerevisiae Q02767 242 27684 Y67 D S I D D T Q Y T N T V D K L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.6 99.5 93.6 N.A. 98.6 95.1 N.A. 47.5 N.A. N.A. 86.5 N.A. 59.7 67.8 42.9 59.3
Protein Similarity: 100 85.4 100 95.4 N.A. 100 96.9 N.A. 54.7 N.A. N.A. 93.7 N.A. 77.8 85.5 61.9 80.8
P-Site Identity: 100 100 100 20 N.A. 86.6 86.6 N.A. 6.6 N.A. N.A. 80 N.A. 6.6 20 6.6 53.3
P-Site Similarity: 100 100 100 40 N.A. 100 100 N.A. 20 N.A. N.A. 93.3 N.A. 20 40 20 66.6
Percent
Protein Identity: 36.6 N.A. N.A. 38.9 28.5 N.A.
Protein Similarity: 59.7 N.A. N.A. 59.7 52.8 N.A.
P-Site Identity: 0 N.A. N.A. 0 26.6 N.A.
P-Site Similarity: 6.6 N.A. N.A. 6.6 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 7 7 7 0 0 7 47 54 14 7 0 0 % A
% Cys: 14 40 0 0 0 0 0 0 0 7 0 47 0 0 0 % C
% Asp: 54 0 14 14 7 0 0 0 0 0 7 0 20 0 0 % D
% Glu: 0 0 0 0 0 0 47 0 14 0 0 7 0 0 0 % E
% Phe: 7 0 0 0 7 0 0 0 0 0 14 14 7 0 0 % F
% Gly: 0 0 7 0 0 0 0 0 0 20 0 0 0 0 14 % G
% His: 0 7 0 0 0 0 0 0 0 0 0 0 0 7 0 % H
% Ile: 0 0 14 7 0 0 0 14 0 0 0 0 0 0 0 % I
% Lys: 7 20 7 0 0 14 7 0 7 0 0 0 7 14 0 % K
% Leu: 14 7 0 14 14 0 0 0 0 0 0 7 0 0 54 % L
% Met: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 20 7 0 0 7 0 0 0 0 0 % N
% Pro: 0 0 0 7 47 14 7 0 0 0 7 7 0 14 0 % P
% Gln: 0 0 0 0 7 0 27 0 7 0 0 0 0 14 0 % Q
% Arg: 0 0 7 0 0 0 0 0 7 14 7 0 7 40 0 % R
% Ser: 0 20 0 20 0 20 7 7 0 0 7 0 47 0 7 % S
% Thr: 0 0 0 34 0 7 0 0 60 0 7 0 0 14 0 % T
% Val: 0 0 54 0 14 14 0 14 0 0 0 7 7 0 14 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 7 0 67 0 0 0 0 0 0 14 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _