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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCNL1 All Species: 24.55
Human Site: S474 Identified Species: 45
UniProt: Q9UK58 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UK58 NP_064703.1 526 59634 S474 R K K S R S R S Q S K S R D H
Chimpanzee Pan troglodytes XP_001151876 508 57500 S460 R S R S Q S K S R D H S D A A
Rhesus Macaque Macaca mulatta XP_001103859 428 47735 D382 P Y N G V R K D S K R S R N S
Dog Lupus familis XP_542852 457 52946 D411 R S Q S K S R D H S D A A K K
Cat Felis silvestris
Mouse Mus musculus Q52KE7 532 60115 S480 R K K S R S R S Q S K T R D H
Rat Rattus norvegicus Q9R1Q2 527 59772 S475 R K K S R S R S Q S K T R D H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520708 508 57907 S456 R K K S R S R S Q S K S R D H
Chicken Gallus gallus Q5ZJP9 534 59812 S480 R K S R S R S S S R S R S R S
Frog Xenopus laevis Q6GN15 496 57208 S448 K S H S P S K S R E P S E L A
Zebra Danio Brachydanio rerio Q7ZVX0 498 57387 D448 N S R E R V R D R D H I K H K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790064 530 60514 T448 H K T K R N R T P P R G Y S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWV3 416 47537 R370 D R D S D R E R D K L K D R S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7RX84 1010 113982 T840 I R R G R S G T R S R S R S Y
Conservation
Percent
Protein Identity: 100 96.5 79.6 85.5 N.A. 96.9 97.9 N.A. 91.6 59.9 79.6 61.2 N.A. N.A. N.A. N.A. 50.5
Protein Similarity: 100 96.5 80.2 86.3 N.A. 97.7 98.8 N.A. 94.1 73.4 86.1 75.2 N.A. N.A. N.A. N.A. 63.5
P-Site Identity: 100 33.3 13.3 33.3 N.A. 93.3 93.3 N.A. 100 20 26.6 13.3 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 60 33.3 53.3 N.A. 100 100 N.A. 100 20 46.6 33.3 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. 32.5 N.A. 20.7
Protein Similarity: N.A. N.A. N.A. 43.9 N.A. 31.6
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. 33.3
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. 73.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 8 8 8 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 8 0 8 0 0 24 8 16 8 0 16 31 0 % D
% Glu: 0 0 0 8 0 0 8 0 0 8 0 0 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 16 0 0 8 0 0 0 0 8 0 0 0 % G
% His: 8 0 8 0 0 0 0 0 8 0 16 0 0 8 31 % H
% Ile: 8 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % I
% Lys: 8 47 31 8 8 0 24 0 0 16 31 8 8 8 16 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 8 0 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 8 0 0 8 0 0 0 0 0 0 0 8 0 % N
% Pro: 8 0 0 0 8 0 0 0 8 8 8 0 0 0 0 % P
% Gln: 0 0 8 0 8 0 0 0 31 0 0 0 0 0 0 % Q
% Arg: 54 16 24 8 54 24 54 8 31 8 24 8 47 16 0 % R
% Ser: 0 31 8 62 8 62 8 54 16 47 8 47 8 16 31 % S
% Thr: 0 0 8 0 0 0 0 16 0 0 0 16 0 0 0 % T
% Val: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 0 0 8 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _