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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DBR1 All Species: 20.61
Human Site: S412 Identified Species: 32.38
UniProt: Q9UK59 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UK59 NP_057300.2 544 61555 S412 N D S G E D Q S E Y N T D T S
Chimpanzee Pan troglodytes XP_526319 545 61694 S412 N D S G E D R S E Y N T D T S
Rhesus Macaque Macaca mulatta XP_001114637 544 61581 S412 N D S G E D R S E Y N T D T S
Dog Lupus familis XP_852077 544 61645 S412 N D S G E D R S E Y N T D T S
Cat Felis silvestris
Mouse Mus musculus Q923B1 550 62271 S413 E E S E E D R S E Y N T D T S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519946 524 58844 D381 G S V E E P S D Y N T D T S G
Chicken Gallus gallus Q5ZLM2 536 60758 P412 S S G S A E E P S E Y N T D N
Frog Xenopus laevis Q6GPB8 534 61070 D408 D S I G S A E D P G E Y S T D
Zebra Danio Brachydanio rerio Q7T3E4 568 62871 S414 T G S A D E P S D F P S D T S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VSD7 534 59444 P404 Q P K V Q L N P Q S N T F C A
Honey Bee Apis mellifera XP_623894 478 54582 V351 P D A I D I S V E P P Q L L V
Nematode Worm Caenorhab. elegans Q966M6 500 56663 A372 R K D F R P T A E E L K E I E
Sea Urchin Strong. purpuratus XP_782666 646 72191 D412 S D D G N D A D D D T S E S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q94K01 418 48157 R295 S I F P L T R R Y T N V S T A
Baker's Yeast Sacchar. cerevisiae P24309 405 47723 Q282 R S G I M N C Q E E N E Y D S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 98.7 90.2 N.A. 85.4 N.A. N.A. 67.6 71.5 64.8 56.5 N.A. 35.6 45.9 35.2 43
Protein Similarity: 100 99.6 99 95.5 N.A. 90.9 N.A. N.A. 77.9 82.5 80.1 70.9 N.A. 51.8 61 53.1 58.6
P-Site Identity: 100 93.3 93.3 93.3 N.A. 73.3 N.A. N.A. 6.6 0 13.3 33.3 N.A. 13.3 13.3 6.6 26.6
P-Site Similarity: 100 100 100 100 N.A. 86.6 N.A. N.A. 13.3 26.6 26.6 66.6 N.A. 33.3 26.6 20 60
Percent
Protein Identity: N.A. N.A. N.A. 41.5 29.4 N.A.
Protein Similarity: N.A. N.A. N.A. 54.7 47.9 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 7 7 7 7 7 0 0 0 0 0 0 14 % A
% Cys: 0 0 0 0 0 0 7 0 0 0 0 0 0 7 0 % C
% Asp: 7 40 14 0 14 40 0 20 14 7 0 7 40 14 7 % D
% Glu: 7 7 0 14 40 14 14 0 54 20 7 7 14 0 7 % E
% Phe: 0 0 7 7 0 0 0 0 0 7 0 0 7 0 0 % F
% Gly: 7 7 14 40 0 0 0 0 0 7 0 0 0 0 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 7 14 0 7 0 0 0 0 0 0 0 7 0 % I
% Lys: 0 7 7 0 0 0 0 0 0 0 0 7 0 0 0 % K
% Leu: 0 0 0 0 7 7 0 0 0 0 7 0 7 7 0 % L
% Met: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 27 0 0 0 7 7 7 0 0 7 54 7 0 0 7 % N
% Pro: 7 7 0 7 0 14 7 14 7 7 14 0 0 0 0 % P
% Gln: 7 0 0 0 7 0 7 7 7 0 0 7 0 0 0 % Q
% Arg: 14 0 0 0 7 0 34 7 0 0 0 0 0 0 0 % R
% Ser: 20 27 40 7 7 0 14 40 7 7 0 14 14 14 54 % S
% Thr: 7 0 0 0 0 7 7 0 0 7 14 40 14 54 0 % T
% Val: 0 0 7 7 0 0 0 7 0 0 0 7 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 14 34 7 7 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _