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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DBR1 All Species: 24.85
Human Site: S478 Identified Species: 39.05
UniProt: Q9UK59 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UK59 NP_057300.2 544 61555 S478 L P G S M I V S S D D T V D S
Chimpanzee Pan troglodytes XP_526319 545 61694 S479 L P G S M I V S S D D T V D S
Rhesus Macaque Macaca mulatta XP_001114637 544 61581 S479 L P G S M I V S S D D T V D S
Dog Lupus familis XP_852077 544 61645 S480 L P G S M I V S S D D T L G S
Cat Felis silvestris
Mouse Mus musculus Q923B1 550 62271 S484 L P S S M F V S S D D A S R S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519946 524 58844 S458 L P D S M T V S S D D T M D S
Chicken Gallus gallus Q5ZLM2 536 60758 A477 M A V S S D D A M D S T N E E
Frog Xenopus laevis Q6GPB8 534 61070 S473 L P D S M A V S S D D A T D S
Zebra Danio Brachydanio rerio Q7T3E4 568 62871 P485 T A K R L I L P A P C A K P K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VSD7 534 59444 S470 T K R K L N L S L P A P T T A
Honey Bee Apis mellifera XP_623894 478 54582 I416 A S F D E D N I L N S T F D G
Nematode Worm Caenorhab. elegans Q966M6 500 56663 K438 L N Q M L V E K T S E H V G T
Sea Urchin Strong. purpuratus XP_782666 646 72191 P529 K T P S I P S P S S G L D N S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q94K01 418 48157 G360 L S L L E L L G L P Y L L D S
Baker's Yeast Sacchar. cerevisiae P24309 405 47723 K347 L V I C Q K N K N L L S N K P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 98.7 90.2 N.A. 85.4 N.A. N.A. 67.6 71.5 64.8 56.5 N.A. 35.6 45.9 35.2 43
Protein Similarity: 100 99.6 99 95.5 N.A. 90.9 N.A. N.A. 77.9 82.5 80.1 70.9 N.A. 51.8 61 53.1 58.6
P-Site Identity: 100 100 100 86.6 N.A. 66.6 N.A. N.A. 80 20 73.3 6.6 N.A. 6.6 13.3 13.3 20
P-Site Similarity: 100 100 100 93.3 N.A. 66.6 N.A. N.A. 86.6 40 73.3 26.6 N.A. 26.6 20 46.6 33.3
Percent
Protein Identity: N.A. N.A. N.A. 41.5 29.4 N.A.
Protein Similarity: N.A. N.A. N.A. 54.7 47.9 N.A.
P-Site Identity: N.A. N.A. N.A. 20 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 14 0 0 0 7 0 7 7 0 7 20 0 0 7 % A
% Cys: 0 0 0 7 0 0 0 0 0 0 7 0 0 0 0 % C
% Asp: 0 0 14 7 0 14 7 0 0 54 47 0 7 47 0 % D
% Glu: 0 0 0 0 14 0 7 0 0 0 7 0 0 7 7 % E
% Phe: 0 0 7 0 0 7 0 0 0 0 0 0 7 0 0 % F
% Gly: 0 0 27 0 0 0 0 7 0 0 7 0 0 14 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % H
% Ile: 0 0 7 0 7 34 0 7 0 0 0 0 0 0 0 % I
% Lys: 7 7 7 7 0 7 0 14 0 0 0 0 7 7 7 % K
% Leu: 67 0 7 7 20 7 20 0 20 7 7 14 14 0 0 % L
% Met: 7 0 0 7 47 0 0 0 7 0 0 0 7 0 0 % M
% Asn: 0 7 0 0 0 7 14 0 7 7 0 0 14 7 0 % N
% Pro: 0 47 7 0 0 7 0 14 0 20 0 7 0 7 7 % P
% Gln: 0 0 7 0 7 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 7 7 0 0 0 0 0 0 0 0 0 7 0 % R
% Ser: 0 14 7 60 7 0 7 54 54 14 14 7 7 0 60 % S
% Thr: 14 7 0 0 0 7 0 0 7 0 0 47 14 7 7 % T
% Val: 0 7 7 0 0 7 47 0 0 0 0 0 27 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _