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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DBR1 All Species: 22.73
Human Site: T192 Identified Species: 35.71
UniProt: Q9UK59 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UK59 NP_057300.2 544 61555 T192 N K K Q L L K T K S F F R Q E
Chimpanzee Pan troglodytes XP_526319 545 61694 T192 N K K Q L L K T K S F F R Q E
Rhesus Macaque Macaca mulatta XP_001114637 544 61581 T192 N K K Q L L K T K S F F R Q E
Dog Lupus familis XP_852077 544 61645 T192 N K K Q L L K T K S F F R Q E
Cat Felis silvestris
Mouse Mus musculus Q923B1 550 62271 T192 N K K Q L L K T K S F F R Q E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519946 524 58844 T162 N K K K L L K T K S F F R Q E
Chicken Gallus gallus Q5ZLM2 536 60758 M192 N K K Q L L K M K S F F R Q E
Frog Xenopus laevis Q6GPB8 534 61070 K192 N K K Q L L K K K D F F R Q E
Zebra Danio Brachydanio rerio Q7T3E4 568 62871 Q192 N T N A L L R Q K K F L R Q E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VSD7 534 59444 K192 N K A Q L L R K K P F F A A D
Honey Bee Apis mellifera XP_623894 478 54582 F159 H I R N L E I F R L K Q L T G
Nematode Worm Caenorhab. elegans Q966M6 500 56663 A161 R F A N L R I A G L S G I F S
Sea Urchin Strong. purpuratus XP_782666 646 72191 K192 N R D E L F R K K S F F E R E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q94K01 418 48157 I104 G G W A A T N I Y F L G F A G
Baker's Yeast Sacchar. cerevisiae P24309 405 47723 H91 G N H E S M R H L M L L P H G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 98.7 90.2 N.A. 85.4 N.A. N.A. 67.6 71.5 64.8 56.5 N.A. 35.6 45.9 35.2 43
Protein Similarity: 100 99.6 99 95.5 N.A. 90.9 N.A. N.A. 77.9 82.5 80.1 70.9 N.A. 51.8 61 53.1 58.6
P-Site Identity: 100 100 100 100 N.A. 100 N.A. N.A. 93.3 93.3 86.6 53.3 N.A. 53.3 6.6 6.6 46.6
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 100 93.3 86.6 60 N.A. 66.6 26.6 6.6 73.3
Percent
Protein Identity: N.A. N.A. N.A. 41.5 29.4 N.A.
Protein Similarity: N.A. N.A. N.A. 54.7 47.9 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 14 14 7 0 0 7 0 0 0 0 7 14 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 0 0 0 0 0 7 0 0 0 0 7 % D
% Glu: 0 0 0 14 0 7 0 0 0 0 0 0 7 0 67 % E
% Phe: 0 7 0 0 0 7 0 7 0 7 74 67 7 7 0 % F
% Gly: 14 7 0 0 0 0 0 0 7 0 0 14 0 0 20 % G
% His: 7 0 7 0 0 0 0 7 0 0 0 0 0 7 0 % H
% Ile: 0 7 0 0 0 0 14 7 0 0 0 0 7 0 0 % I
% Lys: 0 60 54 7 0 0 54 20 74 7 7 0 0 0 0 % K
% Leu: 0 0 0 0 87 67 0 0 7 14 14 14 7 0 0 % L
% Met: 0 0 0 0 0 7 0 7 0 7 0 0 0 0 0 % M
% Asn: 74 7 7 14 0 0 7 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 7 0 0 7 0 0 % P
% Gln: 0 0 0 54 0 0 0 7 0 0 0 7 0 60 0 % Q
% Arg: 7 7 7 0 0 7 27 0 7 0 0 0 60 7 0 % R
% Ser: 0 0 0 0 7 0 0 0 0 54 7 0 0 0 7 % S
% Thr: 0 7 0 0 0 7 0 40 0 0 0 0 0 7 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _