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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DBR1
All Species:
26.97
Human Site:
T418
Identified Species:
42.38
UniProt:
Q9UK59
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UK59
NP_057300.2
544
61555
T418
Q
S
E
Y
N
T
D
T
S
A
L
S
S
I
N
Chimpanzee
Pan troglodytes
XP_526319
545
61694
T418
R
S
E
Y
N
T
D
T
S
A
L
S
S
I
N
Rhesus Macaque
Macaca mulatta
XP_001114637
544
61581
T418
R
S
E
Y
N
T
D
T
S
A
L
S
S
I
N
Dog
Lupus familis
XP_852077
544
61645
T418
R
S
E
Y
N
T
D
T
S
A
L
S
S
I
N
Cat
Felis silvestris
Mouse
Mus musculus
Q923B1
550
62271
T419
R
S
E
Y
N
T
D
T
S
A
L
S
S
I
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519946
524
58844
S387
S
D
Y
N
T
D
T
S
G
L
S
S
S
V
N
Chicken
Gallus gallus
Q5ZLM2
536
60758
D418
E
P
S
E
Y
N
T
D
N
S
G
L
S
S
I
Frog
Xenopus laevis
Q6GPB8
534
61070
T414
E
D
P
G
E
Y
S
T
D
T
S
I
L
S
T
Zebra Danio
Brachydanio rerio
Q7T3E4
568
62871
T420
P
S
D
F
P
S
D
T
S
G
L
S
S
S
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VSD7
534
59444
C410
N
P
Q
S
N
T
F
C
A
T
L
G
I
D
D
Honey Bee
Apis mellifera
XP_623894
478
54582
L357
S
V
E
P
P
Q
L
L
V
N
I
Q
T
T
H
Nematode Worm
Caenorhab. elegans
Q966M6
500
56663
I378
T
A
E
E
L
K
E
I
E
K
L
G
D
L
T
Sea Urchin
Strong. purpuratus
XP_782666
646
72191
S418
A
D
D
D
T
S
E
S
S
R
I
L
F
E
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94K01
418
48157
T301
R
R
Y
T
N
V
S
T
A
G
T
I
Q
E
S
Baker's Yeast
Sacchar. cerevisiae
P24309
405
47723
D288
C
Q
E
E
N
E
Y
D
S
K
Y
G
E
T
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
98.7
90.2
N.A.
85.4
N.A.
N.A.
67.6
71.5
64.8
56.5
N.A.
35.6
45.9
35.2
43
Protein Similarity:
100
99.6
99
95.5
N.A.
90.9
N.A.
N.A.
77.9
82.5
80.1
70.9
N.A.
51.8
61
53.1
58.6
P-Site Identity:
100
93.3
93.3
93.3
N.A.
93.3
N.A.
N.A.
20
6.6
6.6
46.6
N.A.
20
6.6
13.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
33.3
26.6
13.3
66.6
N.A.
40
26.6
33.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.5
29.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.7
47.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
0
0
0
0
14
34
0
0
0
0
0
% A
% Cys:
7
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
20
14
7
0
7
40
14
7
0
0
0
7
7
7
% D
% Glu:
14
0
54
20
7
7
14
0
7
0
0
0
7
14
0
% E
% Phe:
0
0
0
7
0
0
7
0
0
0
0
0
7
0
0
% F
% Gly:
0
0
0
7
0
0
0
0
7
14
7
20
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
0
0
0
0
0
7
0
0
14
14
7
34
7
% I
% Lys:
0
0
0
0
0
7
0
0
0
14
0
0
0
0
0
% K
% Leu:
0
0
0
0
7
0
7
7
0
7
54
14
7
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
7
54
7
0
0
7
7
0
0
0
0
40
% N
% Pro:
7
14
7
7
14
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
7
7
0
0
7
0
0
0
0
0
7
7
0
0
% Q
% Arg:
34
7
0
0
0
0
0
0
0
7
0
0
0
0
7
% R
% Ser:
14
40
7
7
0
14
14
14
54
7
14
47
54
20
14
% S
% Thr:
7
0
0
7
14
40
14
54
0
14
7
0
7
14
14
% T
% Val:
0
7
0
0
0
7
0
0
7
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
14
34
7
7
7
0
0
0
7
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _