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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DBR1 All Species: 10.61
Human Site: T449 Identified Species: 16.67
UniProt: Q9UK59 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UK59 NP_057300.2 544 61555 T449 S A H S G M N T P S V E P S D
Chimpanzee Pan troglodytes XP_526319 545 61694 T450 S A H S G M N T P S V E P S D
Rhesus Macaque Macaca mulatta XP_001114637 544 61581 T450 S A H S D M N T P S V E P S D
Dog Lupus familis XP_852077 544 61645 P451 T R S D M N T P S A E P S S D
Cat Felis silvestris
Mouse Mus musculus Q923B1 550 62271 P455 A H S D M N T P S V E P A S D
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519946 524 58844 S429 R G E P N A S S V E P A S P D
Chicken Gallus gallus Q5ZLM2 536 60758 P448 L S T C S V D P S P D H P P E
Frog Xenopus laevis Q6GPB8 534 61070 K444 E D E G I A E K L G E P S P E
Zebra Danio Brachydanio rerio Q7T3E4 568 62871 A456 G E G K G M D A V V P E G Q V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VSD7 534 59444 R441 G A T E C K D R E T K S S K L
Honey Bee Apis mellifera XP_623894 478 54582 F387 L M N N T K E F K S N E S L M
Nematode Worm Caenorhab. elegans Q966M6 500 56663 P409 T E S S K N V P P S A Y Y R N
Sea Urchin Strong. purpuratus XP_782666 646 72191 P500 G K V A V Q S P S N Q D F P P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q94K01 418 48157 P331 F E F A R T V P A Y N P S Q R
Baker's Yeast Sacchar. cerevisiae P24309 405 47723 T318 I L E I E P D T S H A S W K D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 98.7 90.2 N.A. 85.4 N.A. N.A. 67.6 71.5 64.8 56.5 N.A. 35.6 45.9 35.2 43
Protein Similarity: 100 99.6 99 95.5 N.A. 90.9 N.A. N.A. 77.9 82.5 80.1 70.9 N.A. 51.8 61 53.1 58.6
P-Site Identity: 100 100 93.3 13.3 N.A. 13.3 N.A. N.A. 6.6 6.6 0 20 N.A. 6.6 13.3 20 0
P-Site Similarity: 100 100 93.3 26.6 N.A. 20 N.A. N.A. 20 33.3 6.6 26.6 N.A. 20 26.6 33.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. 41.5 29.4 N.A.
Protein Similarity: N.A. N.A. N.A. 54.7 47.9 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 27 0 14 0 14 0 7 7 7 14 7 7 0 0 % A
% Cys: 0 0 0 7 7 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 14 7 0 27 0 0 0 7 7 0 0 47 % D
% Glu: 7 20 20 7 7 0 14 0 7 7 20 34 0 0 14 % E
% Phe: 7 0 7 0 0 0 0 7 0 0 0 0 7 0 0 % F
% Gly: 20 7 7 7 20 0 0 0 0 7 0 0 7 0 0 % G
% His: 0 7 20 0 0 0 0 0 0 7 0 7 0 0 0 % H
% Ile: 7 0 0 7 7 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 7 0 7 7 14 0 7 7 0 7 0 0 14 0 % K
% Leu: 14 7 0 0 0 0 0 0 7 0 0 0 0 7 7 % L
% Met: 0 7 0 0 14 27 0 0 0 0 0 0 0 0 7 % M
% Asn: 0 0 7 7 7 20 20 0 0 7 14 0 0 0 7 % N
% Pro: 0 0 0 7 0 7 0 40 27 7 14 27 27 27 7 % P
% Gln: 0 0 0 0 0 7 0 0 0 0 7 0 0 14 0 % Q
% Arg: 7 7 0 0 7 0 0 7 0 0 0 0 0 7 7 % R
% Ser: 20 7 20 27 7 0 14 7 34 34 0 14 40 34 0 % S
% Thr: 14 0 14 0 7 7 14 27 0 7 0 0 0 0 0 % T
% Val: 0 0 7 0 7 7 14 0 14 14 20 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 7 0 7 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _