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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FEM1B
All Species:
30
Human Site:
Y267
Identified Species:
60
UniProt:
Q9UK73
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UK73
NP_056137.1
627
70264
Y267
F
A
N
D
R
E
N
Y
D
I
I
K
T
Y
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001083166
564
63568
Y239
V
L
P
P
I
H
A
Y
G
N
R
T
E
C
R
Dog
Lupus familis
XP_535526
720
79995
Y360
F
A
N
D
R
E
N
Y
D
I
M
K
T
Y
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2G0
627
70205
Y267
F
A
N
D
R
E
N
Y
D
I
M
K
T
Y
H
Rat
Rattus norvegicus
P0C6P7
627
70219
Y267
F
A
N
D
R
E
N
Y
D
I
M
K
T
Y
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516065
613
68642
Y253
F
A
N
D
R
E
N
Y
D
I
L
K
T
Y
H
Chicken
Gallus gallus
Q5ZM55
627
70376
Y267
F
A
N
D
R
E
N
Y
D
I
M
K
T
Y
H
Frog
Xenopus laevis
Q6GPE5
629
70256
Y269
F
A
N
D
R
E
N
Y
N
I
T
K
T
Y
Q
Zebra Danio
Brachydanio rerio
Q7T3P8
618
68460
L262
F
V
D
K
K
R
D
L
L
G
A
L
Q
Y
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1ZBY1
650
73029
Y271
Y
A
N
D
K
I
K
Y
D
V
N
K
A
Y
G
Honey Bee
Apis mellifera
XP_397133
451
51452
K132
A
N
V
N
H
P
T
K
S
L
S
T
P
L
R
Nematode Worm
Caenorhab. elegans
P17221
656
74268
A268
L
L
D
K
K
M
D
A
M
S
A
M
N
C
W
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
87.8
86.1
N.A.
99
99.1
N.A.
79.2
90.7
82.8
39.2
N.A.
39
37.6
30.1
N.A.
Protein Similarity:
100
N.A.
89.1
86.5
N.A.
99.8
99.8
N.A.
87.4
96.1
91.5
59.4
N.A.
56
50.8
46.9
N.A.
P-Site Identity:
100
N.A.
6.6
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
80
13.3
N.A.
46.6
0
0
N.A.
P-Site Similarity:
100
N.A.
6.6
100
N.A.
100
100
N.A.
100
100
86.6
33.3
N.A.
66.6
13.3
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
67
0
0
0
0
9
9
0
0
17
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% C
% Asp:
0
0
17
67
0
0
17
0
59
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
59
0
0
0
0
0
0
9
0
0
% E
% Phe:
67
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
9
% G
% His:
0
0
0
0
9
9
0
0
0
0
0
0
0
0
50
% H
% Ile:
0
0
0
0
9
9
0
0
0
59
9
0
0
0
0
% I
% Lys:
0
0
0
17
25
0
9
9
0
0
0
67
0
0
0
% K
% Leu:
9
17
0
0
0
0
0
9
9
9
9
9
0
9
0
% L
% Met:
0
0
0
0
0
9
0
0
9
0
34
9
0
0
0
% M
% Asn:
0
9
67
9
0
0
59
0
9
9
9
0
9
0
0
% N
% Pro:
0
0
9
9
0
9
0
0
0
0
0
0
9
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% Q
% Arg:
0
0
0
0
59
9
0
0
0
0
9
0
0
0
17
% R
% Ser:
0
0
0
0
0
0
0
0
9
9
9
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
9
0
0
0
9
17
59
0
0
% T
% Val:
9
9
9
0
0
0
0
0
0
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% W
% Tyr:
9
0
0
0
0
0
0
75
0
0
0
0
0
75
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _