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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP21
All Species:
22.42
Human Site:
S171
Identified Species:
49.33
UniProt:
Q9UK80
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UK80
NP_001014443.1
565
62656
S171
P
G
P
P
T
L
F
S
I
R
T
E
P
P
A
Chimpanzee
Pan troglodytes
XP_001173040
551
61087
S171
P
G
P
P
T
L
F
S
I
R
T
E
P
P
A
Rhesus Macaque
Macaca mulatta
XP_001117772
565
62621
S171
P
G
P
P
T
L
F
S
I
R
T
E
P
P
A
Dog
Lupus familis
XP_536136
686
74353
S292
P
G
P
P
T
L
L
S
I
R
T
E
P
P
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZL6
566
62654
S171
P
G
P
P
T
L
L
S
I
R
T
E
P
P
T
Rat
Rattus norvegicus
B2GUX4
565
62681
S171
P
G
P
P
T
L
L
S
I
R
T
E
P
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O57429
357
40913
Frog
Xenopus laevis
Q6DCJ1
523
60090
R162
L
L
Q
H
N
P
K
R
R
K
I
T
T
N
C
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
K149
R
H
N
P
K
R
R
K
I
T
A
N
C
T
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392493
643
70321
T263
R
R
P
L
S
S
S
T
V
L
N
S
G
H
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32571
926
105173
N521
M
N
L
N
M
N
S
N
G
H
S
S
A
T
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
99.8
79.5
N.A.
96.4
96.6
N.A.
N.A.
32.2
22.2
22.6
N.A.
N.A.
31.7
N.A.
N.A.
Protein Similarity:
100
97.3
99.8
80.4
N.A.
97.3
97.6
N.A.
N.A.
45.3
37.1
38.2
N.A.
N.A.
44.7
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
N.A.
0
0
13.3
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
N.A.
0
6.6
13.3
N.A.
N.A.
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
34.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
37
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
55
0
0
0
% E
% Phe:
0
0
0
0
0
0
28
0
0
0
0
0
0
0
0
% F
% Gly:
0
55
0
0
0
0
0
0
10
0
0
0
10
0
0
% G
% His:
0
10
0
10
0
0
0
0
0
10
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
64
0
10
0
0
0
10
% I
% Lys:
0
0
0
0
10
0
10
10
0
10
0
0
0
0
0
% K
% Leu:
10
10
10
10
0
55
28
0
0
10
0
0
0
0
0
% L
% Met:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
10
10
10
10
0
10
0
0
10
10
0
10
0
% N
% Pro:
55
0
64
64
0
10
0
0
0
0
0
0
55
55
10
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
19
10
0
0
0
10
10
10
10
55
0
0
0
0
0
% R
% Ser:
0
0
0
0
10
10
19
55
0
0
10
19
0
0
10
% S
% Thr:
0
0
0
0
55
0
0
10
0
10
55
10
10
19
19
% T
% Val:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _