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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP21
All Species:
18.18
Human Site:
S431
Identified Species:
40
UniProt:
Q9UK80
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UK80
NP_001014443.1
565
62656
S431
T
K
E
E
E
L
E
S
E
N
A
P
V
C
D
Chimpanzee
Pan troglodytes
XP_001173040
551
61087
A410
P
I
P
K
K
G
F
A
G
G
K
V
S
L
R
Rhesus Macaque
Macaca mulatta
XP_001117772
565
62621
S431
T
K
E
E
E
L
E
S
E
N
A
P
V
C
D
Dog
Lupus familis
XP_536136
686
74353
S552
T
K
E
E
E
L
E
S
E
N
A
P
V
C
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZL6
566
62654
S432
T
K
E
E
E
L
E
S
E
N
A
P
V
C
D
Rat
Rattus norvegicus
B2GUX4
565
62681
S431
T
K
E
E
E
L
E
S
E
N
A
P
V
C
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O57429
357
40913
P226
V
L
D
G
D
E
K
P
T
C
C
R
C
K
A
Frog
Xenopus laevis
Q6DCJ1
523
60090
E389
S
G
C
H
S
Y
Q
E
S
T
K
Q
L
T
M
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
Q376
S
Y
Q
E
S
T
K
Q
L
T
M
K
R
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392493
643
70321
K511
E
V
L
D
G
D
E
K
P
T
C
S
K
C
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32571
926
105173
D779
K
C
E
N
L
E
V
D
E
Q
W
L
C
P
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
99.8
79.5
N.A.
96.4
96.6
N.A.
N.A.
32.2
22.2
22.6
N.A.
N.A.
31.7
N.A.
N.A.
Protein Similarity:
100
97.3
99.8
80.4
N.A.
97.3
97.6
N.A.
N.A.
45.3
37.1
38.2
N.A.
N.A.
44.7
N.A.
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
N.A.
0
0
6.6
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
N.A.
20
20
26.6
N.A.
N.A.
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
34.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
46
0
0
0
10
% A
% Cys:
0
10
10
0
0
0
0
0
0
10
19
0
19
55
0
% C
% Asp:
0
0
10
10
10
10
0
10
0
0
0
0
0
0
46
% D
% Glu:
10
0
55
55
46
19
55
10
55
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
10
10
10
0
0
10
10
0
0
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
46
0
10
10
0
19
10
0
0
19
10
10
10
0
% K
% Leu:
0
10
10
0
10
46
0
0
10
0
0
10
10
19
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% M
% Asn:
0
0
0
10
0
0
0
0
0
46
0
0
0
0
0
% N
% Pro:
10
0
10
0
0
0
0
10
10
0
0
46
0
10
10
% P
% Gln:
0
0
10
0
0
0
10
10
0
10
0
10
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
10
% R
% Ser:
19
0
0
0
19
0
0
46
10
0
0
10
10
0
0
% S
% Thr:
46
0
0
0
0
10
0
0
10
28
0
0
0
10
0
% T
% Val:
10
10
0
0
0
0
10
0
0
0
0
10
46
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _