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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP21 All Species: 19.09
Human Site: S472 Identified Species: 42
UniProt: Q9UK80 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UK80 NP_001014443.1 565 62656 S472 R F S A S R G S I K K S S V G
Chimpanzee Pan troglodytes XP_001173040 551 61087 I458 T V Q R F P R I L V L H L N R
Rhesus Macaque Macaca mulatta XP_001117772 565 62621 S472 R F S A S R G S I K K S S V G
Dog Lupus familis XP_536136 686 74353 S593 R F S A S R G S I K K S S V G
Cat Felis silvestris
Mouse Mus musculus Q9QZL6 566 62654 S473 R F S T S R G S I K K S S V G
Rat Rattus norvegicus B2GUX4 565 62681 S472 R F S T S R G S I K K S S V G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus O57429 357 40913 K266 E A R I R A S K L T T F V N F
Frog Xenopus laevis Q6DCJ1 523 60090 M432 S F P L E L D M M P F M A S S
Zebra Danio Brachydanio rerio A6H8I0 506 58102 T416 F P L E L D M T P F M A S S K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392493 643 70321 S551 S P M E R F R S K L N V M V D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32571 926 105173 P834 P F L L D L T P F W A N D F D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.3 99.8 79.5 N.A. 96.4 96.6 N.A. N.A. 32.2 22.2 22.6 N.A. N.A. 31.7 N.A. N.A.
Protein Similarity: 100 97.3 99.8 80.4 N.A. 97.3 97.6 N.A. N.A. 45.3 37.1 38.2 N.A. N.A. 44.7 N.A. N.A.
P-Site Identity: 100 0 100 100 N.A. 93.3 93.3 N.A. N.A. 0 6.6 6.6 N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 100 6.6 100 100 N.A. 93.3 93.3 N.A. N.A. 6.6 20 20 N.A. N.A. 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 34.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 28 0 10 0 0 0 0 10 10 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 10 10 0 0 0 0 0 10 0 19 % D
% Glu: 10 0 0 19 10 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 10 64 0 0 10 10 0 0 10 10 10 10 0 10 10 % F
% Gly: 0 0 0 0 0 0 46 0 0 0 0 0 0 0 46 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 10 46 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 10 10 46 46 0 0 0 10 % K
% Leu: 0 0 19 19 10 19 0 0 19 10 10 0 10 0 0 % L
% Met: 0 0 10 0 0 0 10 10 10 0 10 10 10 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 10 10 0 19 0 % N
% Pro: 10 19 10 0 0 10 0 10 10 10 0 0 0 0 0 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 46 0 10 10 19 46 19 0 0 0 0 0 0 0 10 % R
% Ser: 19 0 46 0 46 0 10 55 0 0 0 46 55 19 10 % S
% Thr: 10 0 0 19 0 0 10 10 0 10 10 0 0 0 0 % T
% Val: 0 10 0 0 0 0 0 0 0 10 0 10 10 55 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _