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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP21
All Species:
19.7
Human Site:
S488
Identified Species:
43.33
UniProt:
Q9UK80
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UK80
NP_001014443.1
565
62656
S488
D
F
P
L
Q
R
L
S
L
G
D
F
A
S
D
Chimpanzee
Pan troglodytes
XP_001173040
551
61087
K474
S
A
S
R
G
S
I
K
K
S
S
V
G
V
D
Rhesus Macaque
Macaca mulatta
XP_001117772
565
62621
S488
D
F
P
L
Q
R
L
S
L
G
D
F
A
S
D
Dog
Lupus familis
XP_536136
686
74353
S609
D
F
P
L
Q
R
L
S
L
G
D
F
A
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZL6
566
62654
S489
D
F
P
L
Q
R
L
S
L
G
D
F
A
S
D
Rat
Rattus norvegicus
B2GUX4
565
62681
S488
D
F
P
L
Q
R
L
S
L
G
D
F
A
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O57429
357
40913
E282
L
K
D
L
D
L
R
E
F
A
S
Q
S
C
N
Frog
Xenopus laevis
Q6DCJ1
523
60090
Y448
E
S
R
M
N
G
Q
Y
Q
Q
P
S
D
S
L
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
Q432
S
R
M
N
G
Q
Y
Q
Q
P
V
D
S
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392493
643
70321
S567
P
L
T
G
L
D
L
S
A
F
A
A
P
R
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32571
926
105173
D850
V
F
P
P
G
V
N
D
D
E
L
P
I
R
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
99.8
79.5
N.A.
96.4
96.6
N.A.
N.A.
32.2
22.2
22.6
N.A.
N.A.
31.7
N.A.
N.A.
Protein Similarity:
100
97.3
99.8
80.4
N.A.
97.3
97.6
N.A.
N.A.
45.3
37.1
38.2
N.A.
N.A.
44.7
N.A.
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
N.A.
6.6
6.6
0
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
N.A.
20
20
20
N.A.
N.A.
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
34.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
10
10
10
10
46
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
46
0
10
0
10
10
0
10
10
0
46
10
10
0
55
% D
% Glu:
10
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% E
% Phe:
0
55
0
0
0
0
0
0
10
10
0
46
0
0
0
% F
% Gly:
0
0
0
10
28
10
0
0
0
46
0
0
10
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% I
% Lys:
0
10
0
0
0
0
0
10
10
0
0
0
0
0
0
% K
% Leu:
10
10
0
55
10
10
55
0
46
0
10
0
0
10
10
% L
% Met:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
10
0
10
0
0
0
0
0
0
0
19
% N
% Pro:
10
0
55
10
0
0
0
0
0
10
10
10
10
0
0
% P
% Gln:
0
0
0
0
46
10
10
10
19
10
0
10
0
0
0
% Q
% Arg:
0
10
10
10
0
46
10
0
0
0
0
0
0
19
0
% R
% Ser:
19
10
10
0
0
10
0
55
0
10
19
10
19
55
0
% S
% Thr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
10
0
0
0
0
10
0
0
0
0
10
10
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _