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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP21
All Species:
21.52
Human Site:
Y505
Identified Species:
47.33
UniProt:
Q9UK80
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UK80
NP_001014443.1
565
62656
Y505
G
S
P
V
Y
Q
L
Y
A
L
C
N
H
S
G
Chimpanzee
Pan troglodytes
XP_001173040
551
61087
D491
L
Q
R
L
S
L
G
D
F
A
S
D
K
A
G
Rhesus Macaque
Macaca mulatta
XP_001117772
565
62621
Y505
G
S
P
V
Y
Q
L
Y
A
L
C
N
H
S
G
Dog
Lupus familis
XP_536136
686
74353
Y626
G
S
P
V
Y
Q
L
Y
A
L
C
N
H
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZL6
566
62654
Y506
G
S
P
V
Y
Q
L
Y
A
L
C
N
H
S
G
Rat
Rattus norvegicus
B2GUX4
565
62681
Y505
G
S
P
V
Y
Q
L
Y
A
L
C
N
H
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O57429
357
40913
S299
V
Y
N
L
Y
A
V
S
N
H
S
G
T
T
M
Frog
Xenopus laevis
Q6DCJ1
523
60090
A465
D
N
K
Y
S
L
F
A
V
V
N
H
Q
G
T
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
V449
N
K
Y
S
L
F
A
V
V
N
H
Q
G
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392493
643
70321
V584
C
T
Y
N
L
Y
G
V
A
N
H
S
G
T
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32571
926
105173
Y867
P
P
F
K
Y
E
L
Y
G
V
A
C
H
F
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
99.8
79.5
N.A.
96.4
96.6
N.A.
N.A.
32.2
22.2
22.6
N.A.
N.A.
31.7
N.A.
N.A.
Protein Similarity:
100
97.3
99.8
80.4
N.A.
97.3
97.6
N.A.
N.A.
45.3
37.1
38.2
N.A.
N.A.
44.7
N.A.
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
N.A.
6.6
0
0
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
N.A.
26.6
20
6.6
N.A.
N.A.
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
34.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
10
10
55
10
10
0
0
10
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
46
10
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% D
% Glu:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
10
0
0
10
10
0
10
0
0
0
0
10
0
% F
% Gly:
46
0
0
0
0
0
19
0
10
0
0
10
19
10
64
% G
% His:
0
0
0
0
0
0
0
0
0
10
19
10
55
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
10
10
0
0
0
0
0
0
0
0
10
0
0
% K
% Leu:
10
0
0
19
19
19
55
0
0
46
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
10
10
10
10
0
0
0
0
10
19
10
46
0
0
0
% N
% Pro:
10
10
46
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
46
0
0
0
0
0
10
10
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
46
0
10
19
0
0
10
0
0
19
10
0
46
0
% S
% Thr:
0
10
0
0
0
0
0
0
0
0
0
0
10
28
19
% T
% Val:
10
0
0
46
0
0
10
19
19
19
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
19
10
64
10
0
55
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _