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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXO10
All Species:
21.82
Human Site:
S318
Identified Species:
48
UniProt:
Q9UK96
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UK96
NP_036298.2
956
105195
S318
I
V
I
E
G
S
Q
S
P
T
S
P
A
S
S
Chimpanzee
Pan troglodytes
XP_520584
1014
111075
S376
I
V
I
E
G
S
Q
S
P
T
S
P
A
S
S
Rhesus Macaque
Macaca mulatta
XP_001111119
1023
112176
S385
I
V
I
E
G
S
Q
S
P
T
S
P
A
S
S
Dog
Lupus familis
XP_538735
963
105501
S325
I
V
I
E
G
S
Q
S
P
T
S
P
A
A
T
Cat
Felis silvestris
Mouse
Mus musculus
NP_001019313
950
104459
S318
I
V
I
E
G
S
Q
S
P
T
S
P
V
C
S
Rat
Rattus norvegicus
XP_001071167
950
104300
S318
I
V
I
E
G
S
Q
S
P
T
S
P
V
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510335
1118
121038
G367
C
E
I
V
I
G
E
G
Q
S
S
F
L
P
T
Chicken
Gallus gallus
XP_419357
1076
118785
E354
R
L
Y
M
E
V
F
E
Y
T
R
P
M
M
H
Frog
Xenopus laevis
NP_001086604
843
94076
D254
V
F
M
E
G
S
E
D
A
Y
V
G
Y
M
T
Zebra Danio
Brachydanio rerio
NP_001128729
964
105168
D321
E
G
I
N
T
M
E
D
W
S
K
P
E
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785605
875
96986
G283
S
T
F
R
F
I
E
G
C
E
D
A
Y
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.1
92.6
95.1
N.A.
93.7
92.8
N.A.
54
20.7
20.6
52.7
N.A.
N.A.
N.A.
N.A.
21.1
Protein Similarity:
100
94.1
93
97.3
N.A.
96.6
96.5
N.A.
66
35
35.8
70.5
N.A.
N.A.
N.A.
N.A.
37.2
P-Site Identity:
100
100
100
86.6
N.A.
86.6
93.3
N.A.
13.3
13.3
20
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
86.6
93.3
N.A.
33.3
20
46.6
26.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
0
10
37
10
0
% A
% Cys:
10
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% C
% Asp:
0
0
0
0
0
0
0
19
0
0
10
0
0
0
10
% D
% Glu:
10
10
0
64
10
0
37
10
0
10
0
0
10
0
0
% E
% Phe:
0
10
10
0
10
0
10
0
0
0
0
10
0
0
0
% F
% Gly:
0
10
0
0
64
10
0
19
0
0
0
10
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
55
0
73
0
10
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
0
10
0
0
0
0
0
0
0
0
0
0
10
10
0
% L
% Met:
0
0
10
10
0
10
0
0
0
0
0
0
10
19
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
55
0
0
73
0
10
0
% P
% Gln:
0
0
0
0
0
0
55
0
10
0
0
0
0
0
0
% Q
% Arg:
10
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
10
0
0
0
0
64
0
55
0
19
64
0
0
37
46
% S
% Thr:
0
10
0
0
10
0
0
0
0
64
0
0
0
0
28
% T
% Val:
10
55
0
10
0
10
0
0
0
0
10
0
19
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
10
10
0
0
19
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _